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18786 Ensembl ENSG00000137055 ENSMUSG00000028577 UniProt Q9Y263 P27612 RefSeq (mRNA) NM_001031689 NM_004253 NM_001321546 NM_172695 RefSeq (protein) NP_001026859 NP_001308475 NP_766283 Location (UCSC) Chr 9: 26.9 – 26.95 Mb Chr 4: 94.46 – 94.49 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Phospholipase A-2-activating protein is an enzyme that in humans is encoded by the PLAA ...
Phospholipases A 2 include several unrelated protein families with common enzymatic activity. Two most notable families are secreted and cytosolic phospholipases A 2. Other families include Ca 2+ independent PLA 2 (iPLA 2) and lipoprotein-associated PLA 2 (Lp-PLA 2), also known as platelet activating factor acetylhydrolase (PAF-AH).
5321 18783 Ensembl ENSG00000116711 ENSMUSG00000056220 UniProt P47712 P47713 RefSeq (mRNA) NM_001311193 NM_024420 NM_008869 NM_001305632 RefSeq (protein) NP_001298122 NP_077734 NP_001292561 NP_032895 Location (UCSC) Chr 1: 186.83 – 186.99 Mb Chr 1: 149.71 – 149.84 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Cytosolic phospholipase A 2 is an enzyme that in humans is encoded by ...
Lipoprotein-associated phospholipase A 2 (Lp-PLA 2) also known as platelet-activating factor acetylhydrolase (PAF-AH) is a phospholipase A 2 enzyme that in humans is encoded by the PLA2G7 gene. [5] [6] Lp-PLA 2 is a 45-kDa protein of 441 amino acids. [7] It is one of several PAF acetylhydrolases.
18778 Ensembl ENSG00000170890 ENSMUSG00000029522 UniProt P04054 Q9Z0Y2 RefSeq (mRNA) NM_000928 NM_011107 NM_001356586 NM_001356587 RefSeq (protein) NP_000919 NP_035237 NP_001343515 NP_001343516 Location (UCSC) Chr 12: 120.32 – 120.33 Mb Chr 5: 115.6 – 115.61 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Phospholipase A 2, group 1B is an enzyme that in humans is encoded by the ...
Group XVI phospholipase A2 also commonly known as adipocyte phospholipase A2 (AdPLA) is an enzyme that in humans is encoded by the PLA2G16 gene. [ 1 ] [ 2 ] [ 3 ] This enzyme has also been identified as PLA2G16, HRASLS3, HREV107, HREV107-3, MGC118754 or H-REV107-1 from studies on class II tumor suppression but not on its enzymatic properties. [ 4 ]
Endothelial lipase is primarily a phospholipase. [2] Phospholipase A 2 acts on the intact lecithin molecule and hydrolyzes the fatty acid esterified to the second carbon atom. The resulting products are lysolecithin and a fatty acid. Phospholipase A 2 is an enzyme present in the venom of bees, blennies and viper snakes. [3]
Ca 2+ is important for cellular signalling, for once it enters the cytosol of the cytoplasm it exerts allosteric regulatory effects on many enzymes and proteins. Ca 2+ can act in signal transduction resulting from activation of ion channels or as a second messenger caused by indirect signal transduction pathways such as G protein-coupled receptors.