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3-Deazaneplanocin A (DZNep, C-c3Ado) is a drug which acts as both a S-adenosylhomocysteine synthesis inhibitor and also a histone methyltransferase EZH2 inhibitor. Studies have shown that it has effects in vitro against a variety of different tumor cell lines.
In addition to 31 P– 31 P coupling between the two types of phosphine centers, 103 Rh– 31 P coupling is also evident. The chemical shifts are referenced to external 85% H 3 PO 4 . Phosphorus-31 NMR spectroscopy is an analytical chemistry technique that uses nuclear magnetic resonance (NMR) to study chemical compounds that contain phosphorus .
Moore was born in Joliet, Illinois while his father, Dr. James P. Moore, was in medical residency. His mother, Dorothy Robinette Woodring Moore, was the head of the World War II Canteen at Joseph Horne Department Store in Pittsburgh and served as an assistant to the legendary Gwilym Price, President and CEO of the Westinghouse Electric Corporation, in the years after the war.