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JWH-018 is a full agonist of both the CB 1 and CB 2 cannabinoid receptors, with a reported binding affinity of 9.00 ± 5.00 nM at CB 1 and 2.94 ± 2.65 nM at CB 2. [6] JWH-018 has an EC 50 of 102 nM for human CB 1 receptors, and 133 nM for human CB 2 receptors. [16]
JWH-018 was banned by controlled substances act on December 21, 2012. Law enforcement officials in Canada asked Huffman to serve as a consultant and expert witness. He received numerous media queries and requests for analytical help from law enforcement officials.
JWH-018, JWH-073, CP 47,497 (and its homologues), and HU-210, as well as leonotis leonurus, have been all banned in Latvia since 2005. [135] After the first confirmed lethal case from the use of legal drugs in late 2013, parliament significantly increased the number of temporarily banned substances used in Spice and similar preparations.
FUB-JWH-018 (also known as FUB-018) is a naphthoylindole-based synthetic cannabinoid, representing a molecular hybrid of JWH-018 and AB-FUBICA or ADB-FUBICA. [ 1 ] [ 2 ] Legal status
JWH-004: Naphthoylindole: 48 ± 13: 4 ± 1.5: CB 2 (12x) JWH-007 [5] Naphthoylindole: 9.5 ± 4.5: 2.9 ± 2.6: CB 2 (3.3x) JWH-009: Naphthoylindole >10000: 141 ± 14: CB 2 (>70x) JWH-011: Naphthoylindole: JWH-015 [5] Naphthoylindole: 164 ± 22: 13.8 ± 4.6: CB 2 (12x) JWH-016: Naphthoylindole: 22 ± 1.5: 4.3 ± 1.6: CB 2 (5.1x) JWH-018 [5 ...
FUBIMINA — the terminally fluorinated (5-fluoro) analogue of BIM-018. MDMB-CHMICA; MDMB-FUBINACA; MMB-2201; MN-18 — the indazole analogue of NNE1. NM-2201 — NNE1 — also known as NNEI, MN-24 and AM-6527, is the carboxamide analogue of JWH-018. NNE1 was first described in a paper by Abbott Laboratories in 2011. [5] PB-22 — PX-1 — PX-2 ...
Section in question: "In most other countries JWH-018 remains legal at present, although it might potentially be deemed a controlled substance analogue in certain jurisdictions where very broadly worded drug analogues laws are in force. JWH-018 is unlike any known illegal cannabinoid, and thus is not subject to various analogue acts."
Reefer Madness: Sex, Drugs, and Cheap Labor in the American Black Market (2003) by Eric Schlosser; Cannabis: A History (2003) by Martin Booth; This Is Your Country On Drugs (2009) by Ryan Grim; The Pot Book (2010) by Julie Holland; Growgirl (2012) by Heather Donahue; The Official High Times Cannabis Cookbook (2012) by Elise McDonough