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Mitral regurgitation, also known as mitral insufficiency or mitral incompetence, is the backward flow of blood from the left ventricle, through the mitral valve, and into the left atrium, when the left ventricle contracts, resulting in a systolic murmur radiating to the left armpit. [5] [3]
Pulmonary (or pulmonic [4]) regurgitation (or insufficiency, incompetence) is a condition in which the pulmonary valve is incompetent [5] and allows backflow from the pulmonary artery to the right ventricle of the heart during diastole. [6] While a small amount of backflow may occur ordinarily, it is usually only shown on an echocardiogram and ...
In the United States, MVP is the most common cause of severe, non-ischemic mitral regurgitation. [4] This is occasionally due to rupture of the chordae tendineae that support the mitral valve. [11] The severity of regurgitation in MVP is typically estimated using a grading system: [16] [17] [18] 0 (none or trivial) Grade 1 (mild) Grade 2 (moderate)
Mitral regurgitation: the backflow of blood from the left ventricle into the left atrium, owing to insufficiency of the mitral valve; it may be acute or chronic, and is usually due to mitral valve prolapse, rheumatic heart disease, or a complication of cardiac dilatation. See also Mitral regurgitation.
Mitral regurgitation may be treated medically with vasodilators, diuretics, digoxin, antiarrhythmics, and chronic anticoagulation. [15] [16] Mild to moderate mitral regurgitation should be followed with echocardiography and cardiac stress test every 1–3 years. [15]
Condition Description Late systolic Mitral valve prolapse: This is the most common cause of late systolic murmurs. It can be heard best over the apex of the heart, usually preceded by clicks. The most common cause of mitral valve prolapse is "floppy" valve (Barlow's) syndrome. If the prolapse becomes severe enough, mitral regurgitation may occur.
The natural history of mitral stenosis secondary to rheumatic fever (the most common cause) is an asymptomatic latent phase following the initial episode of rheumatic fever. This latent period lasts an average of 16.3 ± 5.2 years. Once symptoms of mitral stenosis begin to develop, progression to severe disability takes 9.2 ± 4.3 years.
Common causes include aortic or pulmonary regurgitation and left anterior descending artery stenosis. Mid-diastolic murmurs start after S2 and end before S1. They are due to turbulent flow across the atrioventricular (mitral & tricuspid) valves during the rapid filling phase from mitral or tricuspid stenosis.
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