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Protopanaxadiol (PPD) is an organic compound that is an aglycone of ginsenosides, a group of steroid glycosides. It is a dammarane-type tetracyclic terpene sapogenin found in ginseng (Panax ginseng) and in notoginseng (Panax pseudoginseng). [1] [2] The health effect of protopanaxadiol inside the human body is still unclear.
Smoking most commonly leads to diseases affecting the heart and lungs and will commonly affect areas such as hands or feet. First signs of smoking-related health issues often show up as numbness in the extremities, with smoking being a major risk factor for heart attacks, chronic obstructive pulmonary disease (COPD), emphysema, and cancer, particularly lung cancer, cancers of the larynx and ...
The level of ethanol consumption that minimizes the risk of disease, injury, and death is subject to some controversy. [16] Several studies have found a J-shaped relationship between alcohol consumption and health, [17] [18] [2] [19] meaning that risk is minimized at a certain (non-zero) consumption level, and drinking below or above this level increases risk, with the risk level of drinking a ...
Alcohol abuse was a psychiatric diagnosis in the DSM-IV, but it has been merged with alcohol dependence in the DSM-5 into alcohol use disorder. [2] [3] Globally, excessive alcohol consumption is the seventh leading risk factor for both death and the burden of disease and injury, [4] representing 5.1% of the total global burden of disease and ...
Children less than four years of age, or children and adolescents exposed to adults in high-risk categories; 15 mm or more is positive in Persons with no known risk factors for TB [13] A tuberculin test conversion is defined as an increase of 10 mm or more within a two-year period, regardless of age.
Short-term effects of alcohol consumption include intoxication and dehydration. Long-term effects of alcohol include changes in the metabolism of the liver and brain, with increased risk of several types of cancer and alcohol use disorder. [1] Alcohol intoxication affects the brain, causing slurred speech, clumsiness, and delayed reflexes.
The health effects of tobacco had been debated by users, medical experts, and governments alike since its introduction to European culture. [1] Hard evidence for the ill effects of smoking became apparent with the results of several long-term studies conducted in the early to middle twentieth century, such as the epidemiology studies of Richard Doll and pathology studies of Oscar Auerbach.
For example: a person who has smoked 15 cigarettes a day for 40 years has a (15/20) x 40 = 30 pack-year smoking history. One pack-year is smoking 20 cigarettes a day for one year. If someone has smoked 10 cigarettes a day for 6 years they would have a 3 pack-year history. Someone who has smoked 40 cigarettes (2 packs) daily for 20 years has a ...