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Metformin use is typically associated with weight loss. [68] It appears to be safe and effective in counteracting the weight gain caused by the antipsychotic medications olanzapine and clozapine. [69] [70] [71] Although modest reversal of clozapine-associated weight gain is found with metformin, primary prevention of weight gain is more ...
Metformin is a medication primarily used to manage type 2 diabetes by reducing glucose production in the liver and improving insulin sensitivity. It is also sometimes prescribed for weight ...
Metformin is available to treat type 2 diabetes as-is, and is also used with other drugs in some medications to treat diabetes, according to the U.S. National Library of Medicine. Why it's being ...
5. Metformin. Metformin — a biguanide — is an oral diabetes medication that helps keep blood sugar in check by causing the liver to produce less glucose. It was approved by the FDA in 1994 for ...
Initially phenformin was widely used, but its potential for sometimes fatal lactic acidosis resulted in its withdrawal from most pharmacopeias (in the U.S. in 1978). [6] Metformin has a much better safety profile, and it is the principal biguanide drug used in pharmacotherapy worldwide.
In the United States, sitagliptin/metformin is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes. [5] [6]In the European Union, sitagliptin/metformin is indicated as an adjunct to diet and exercise to improve glycemic control in people with type 2 diabetes; in combination with a sulfonylurea as an adjunct to diet and exercise "in people ...