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The substances cause an increase in the osmotic pressure within the tubule, causing retention of water within the lumen, and thus reduces the reabsorption of water, increasing urine output (i.e., diuresis). The same effect can be seen in therapeutics such as mannitol, which is used to increase urine output and decrease extracellular fluid volume.
Hantavirus hemorrhagic fever with renal syndrome (HFRS) is a hemorrhagic fever caused by hantaviruses.Symptoms occur usually occur 12–16 days after exposure to the virus and come in five distinct phases: febrile, hypotensive, low urine production (oliguric), high urine production (diuretic), and recovery.
In the absence of diabetes mellitus, the most common causes are the decreased secretion of aldosterone due to adrenal cortical tumor, primary polydipsia (excessive fluid drinking), central diabetes insipidus, and nephrogenic diabetes insipidus. [6] Polyuria may also be due to various chemical substances, such as diuretics, caffeine, and ethanol.
The kidney in humans is capable of producing glucose from lactate, glycerol and glutamine. The kidney is responsible for about half of the total gluconeogenesis in fasting humans. The regulation of glucose production in the kidney is achieved by action of insulin, catecholamines and other hormones. [14]
Euvolemia is the state of normal body fluid volume, including blood volume, interstitial fluid volume, and intracellular fluid volume; hypovolemia and hypervolemia are imbalances. Water is necessary for all life on Earth. Humans can survive for 4 to 6 weeks without food but only for a few days without water.
In those in which an underlying cause cannot be found, or is untreatable, treatments are targeted to alleviating correcting the hypoosmolality and hyponatremia. [2] These include restriction of fluid intake, using salt tablets (sometimes with diuretics), urea supplements, intravenous saline, or increasing protein intake. [2]
551 11998 Ensembl ENSG00000101200 ENSMUSG00000037727 UniProt P01185 P35455 RefSeq (mRNA) NM_000490 NM_009732 RefSeq (protein) NP_000481 NP_033862 Location (UCSC) Chr 20: 3.08 – 3.08 Mb Chr 2: 130.42 – 130.42 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Human vasopressin, also called antidiuretic hormone (ADH), arginine vasopressin (AVP) or argipressin, is a hormone synthesized ...
Infected animals can spread the virus to uninfected animals through aerosols or droplets from their feces, urine, saliva, [12] and blood, [19] through consumption of contaminated food, from virus particles shed from skin or fur, [10] via grooming, [4] or through biting and scratching.