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Micrograph of gene transcription of ribosomal RNA illustrating the growing primary transcripts. A primary transcript is the single-stranded ribonucleic acid product synthesized by transcription of DNA, and processed to yield various mature RNA products such as mRNAs, tRNAs, and rRNAs.
The process of transcription is a major source of DNA damage, due to the formation of single-strand DNA intermediates that are vulnerable to damage. [53] The regulation of transcription by processes using base excision repair and/or topoisomerases to cut and remodel the genome also increases the vulnerability of DNA to damage. [53]
The transcription of a basic bacterial gene is dependent on the strength of its promoter and the presence of activators or repressors. In the absence of other regulatory elements, a promoter's sequence-based affinity for RNA polymerases varies, which results in the production of different amounts of transcript.
Transcription and transposition errors are found everywhere, even in professional articles in newspapers or books. They can be missed by editors quite easily, just as they can be created quite easily. The most obvious cure for the errors is for the user to watch the screen when they type, and to proofread.
Several cell function-specific transcription factors (among the about 1,600 transcription factors in a human cell) [68] generally bind to specific motifs on an enhancer. [69] A small combination of these enhancer-bound transcription factors, when brought close to a promoter by a DNA loop, govern transcription level of the target gene.
Some of these transcripts are known to be non-functional because they map to transcribed pseudogenes or degenerative transposons and viruses. Others map to unidentified regions of the genome that may be junk DNA. Spurious transcription is very common in eukaryotes, especially those with large genomes that might contain a lot of junk DNA.
The rho protein then pulls the RNA transcript from the DNA template and the newly synthesized mRNA is released, ending transcription. [ 5 ] [ 1 ] Rho factor is a protein complex that also displays helicase activities (is able to unwind the nucleic acid strands).
Transcription (linguistics), the representations of speech or signing in written form Orthographic transcription, a transcription method that employs the standard spelling system of each target language; Phonetic transcription, the representation of specific speech sounds or sign components; service and software
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