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Most telling perhaps is that 70-80% of breast cancer patients receiving chemotherapy based on traditional predictors would have survived without it. [3] [4] Of note, similar gene expression patterns associated with metastatic behaviour of breast cancer tumor cells have also been found in breast cancer of dog, the most common tumor of the female ...
The Cancer Genome Atlas (TCGA) is a project to catalogue the genomic alterations responsible for cancer using genome sequencing and bioinformatics. [1] [2] The overarching goal was to apply high-throughput genome analysis techniques to improve the ability to diagnose, treat, and prevent cancer through a better understanding of the genetic basis of the disease.
Collecting duct carcinoma (CDC) is a type of kidney cancer that originates in the papillary duct of the kidney. It is rare, accounting for 1-3% of all kidney cancers. [ 2 ] It is also recently described; a 2002 review found just 40 case reports worldwide. [ 3 ]
Hereditary nonpolyposis colorectal cancer (HNPCC) is a hereditary predisposition to colon cancer.. HNPCC includes (and was once synonymous with) [1] Lynch syndrome, an autosomal dominant genetic condition that is associated with a high risk of colon cancer, endometrial cancer (second most common), ovary, stomach, small intestine, hepatobiliary tract, upper urinary tract, brain, and skin. [2]
The hallmarks of cancer were originally six biological capabilities acquired during the multistep development of human tumors and have since been increased to eight capabilities and two enabling capabilities. The idea was coined by Douglas Hanahan and Robert Weinberg in their paper "The Hallmarks of Cancer" published January 2000 in Cell. [1]
But brain cancer was the most common cause of cancer deaths among youths in 2021, according to the CDC report. Death rates for brain cancer that year were 23% higher than for leukemia, and more ...
The instrument closely resembles survey items and topics found on HINTS 5, Cycle 4 (2020), and includes other topics relevant to cancer survivors. A unique aspect of the dataset is that key data elements from the cancer registry datasets are linked to the survey responses, providing a more in-depth view of each respondent's cancer diagnosis.
Triple-negative breast cancer comprises 15–20% of all breast cancer cases [3] and affects more young women or women with a mutation in the BRCA1 gene than other breast cancers. [4] Triple-negative breast cancers comprise a very heterogeneous group of cancers. TNBC is the most challenging breast cancer type to treat. [5]