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  2. Destination therapy - Wikipedia

    en.wikipedia.org/wiki/Destination_therapy

    In 2000, the Randomized Evaluation of Mechanical Assistance for the Treatment of Congestive Heart Failure (REMATCH) trial was conducted. REMATCH was a multi-center study supported by the National Heart, Lung, and Blood Institute to compare long-term implantation of left ventricular assist devices with optimal medical management for patients with end-stage heart failure who require, but do not ...

  3. Ventricular assist device - Wikipedia

    en.wikipedia.org/wiki/Ventricular_assist_device

    The first left ventricular assist device (LVAD) system was created by Domingo Liotta at Baylor College of Medicine in Houston in 1962. The first LVAD was implanted in 1963 by Liotta and E. Stanley Crawford. The first successful implantation of an LVAD was completed in 1966 by Liotta along with Dr. Michael E. DeBakey.

  4. Berlin Heart - Wikipedia

    en.wikipedia.org/wiki/Berlin_Heart

    Berlin Heart manufactures two types of VADs: implantable and paracorporeal. INCOR is an axial-flow pump for support of the left ventricle.In this system, the pump is implanted directly next to the heart and is connected to the heart by cannula.

  5. Prescription drug prices in the United States - Wikipedia

    en.wikipedia.org/wiki/Prescription_drug_prices...

    Prescription drug list prices in the United States continually are among the highest in the world. [1] [2] The high cost of prescription drugs became a major topic of discussion in the 21st century, leading up to the American health care reform debate of 2009, and received renewed attention in 2015.

  6. Transcatheter pulmonary valve replacement - Wikipedia

    en.wikipedia.org/wiki/Transcatheter_pulmonary...

    Transcatheter pulmonary valve replacement (TPVR), also known as percutaneous pulmonary valve implantation (PPVI), is the replacement of the pulmonary valve via catheterization through a vein. It is a significantly less invasive procedure in comparison to open heart surgery and is commonly used to treat conditions such as pulmonary atresia .

  7. Cost of drug development - Wikipedia

    en.wikipedia.org/wiki/Cost_of_drug_development

    In an analysis of the drug development costs for 98 companies over a decade, the average cost per drug developed and approved by a single-drug company was $350 million. [3] But for companies that approved between eight and 13 drugs over 10 years, the cost per drug went as high as $5.5 billion. [3]

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    mail.aol.com

    Get AOL Mail for FREE! Manage your email like never before with travel, photo & document views. Personalize your inbox with themes & tabs. You've Got Mail!

  9. Wearable cardioverter defibrillator - Wikipedia

    en.wikipedia.org/wiki/Wearable_cardioverter...

    Per current guidelines (e.g., the ESC guidelines from 2015 and 2021) a patient has to wait at least 40 to 90 days after the cardiac event (e.g., myocardial infarction or newly diagnosed heart failure with reduced left ventricular function) before the decision to implant an ICD should be made. [21]