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Alpha-1 blocker, blocks alpha receptors and it relaxes the smooth muscles in the bladder. It helps the urine to flow smoothly and it can lessen the pain caused by the bladder pressing on the prostate. [44] [45] Selective alpha-1 blockers are better tolerated than non-selective alpha blockers in the body and therefore works better on BPH. [2]
When the term "alpha blocker" is used without further qualification, it can refer to an α 1 blocker, an α 2 blocker, a nonselective blocker (both α 1 and α 2 activity), or an α blocker with some β activity. [2] However, the most common type of alpha blocker is usually an α 1 blocker. Non-selective α-adrenergic receptor antagonists include:
Prazosin is an α 1-blocker that acts as a non-selective inverse agonist at α 1-adrenergic receptors, including of the α 1A-, α 1B-, and α 1D-adrenergic receptor subtypes. [24] It binds to these receptors with affinity (K i ) values of 0.13 to 1.0 nM for the α 1Α -adrenergic receptor, 0.06 to 0.62 nM for the α 1B -adrenergic receptor ...
Medications for Depression: An Overview. Antidepressants are a class of medications used very commonly to treat depression. In fact, nearly 13 percent of people 12 and over in the U.S. used ...
Alpha-blockers, like prazosin (Minipress®), are typically used to manage high blood pressure. These medications work by blocking the norepinephrine to help prevent blood vessels from tightening ...
Alpha-blockers, which relax blood vessels and are prescribed for hypertension and benign prostatic hyperplasia (BPH), a common prostate condition among aging men that can lead to enlarged prostate ...
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