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The basement membrane, also known as base membrane, is a thin, pliable sheet-like type of extracellular matrix that provides cell and tissue support and acts as a platform for complex signalling. [1] [2] The basement membrane sits between epithelial tissues including mesothelium and endothelium, and the underlying connective tissue. [3] [4]
Some theorize that the lamina lucida is an artifact created when preparing the tissue, and that the lamina lucida is therefore equal to the lamina densa in vivo. [7] The term "basal lamina" is usually used with electron microscopy, while the term "basement membrane" is usually used with light microscopy. Examples of basement membranes include:
Connective tissue is one of the four primary types of animal tissue, a group of cells that are similar in structure, along with epithelial tissue, muscle tissue, and nervous tissue. [1] It develops mostly from the mesenchyme , derived from the mesoderm , the middle embryonic germ layer . [ 2 ]
Mesenchyme (/ ˈ m ɛ s ə n k aɪ m ˈ m iː z ən-/ [1]) is a type of loosely organized animal embryonic connective tissue of undifferentiated cells that give rise to most tissues, such as skin, blood or bone. [2] [3] The interactions between mesenchyme and epithelium help to form nearly every organ in the developing embryo. [4]
Functions of epithelial tissue: The principle function of epithelial tissues are covering and lining of free surface; The cells of the body's surface form the outer layer of skin. Inside the body, epithelial cells form the lining of the mouth and alimentary canal and protect these organs. Epithelial tissues help in the elimination of waste.
Epithelioid cells gather around the focus of necrosis, in direct contact with the necrotic masses, forming a kind of boundary zone.. Structurally, epithelioid cells (when examined by light microscopy after stained with hematoxylin and eosin), are elongated, with finely granular, pale eosinophilic (pink) cytoplasm, and central, ovoid nuclei (oval or elongate), which are less dense than that of ...
Epithelium or epithelial tissue is a thin, continuous, protective layer of cells with little extracellular matrix. An example is the epidermis , the outermost layer of the skin . Epithelial ( mesothelial ) tissues line the outer surfaces of many internal organs , the corresponding inner surfaces of body cavities , and the inner surfaces of ...
Basement membranes are sheet-like depositions of ECM on which various epithelial cells rest. Each type of connective tissue in animals has a type of ECM: collagen fibers and bone mineral comprise the ECM of bone tissue; reticular fibers and ground substance comprise the ECM of loose connective tissue; and blood plasma is the ECM of blood.