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All of them are different with three exceptions: one protein is found in both subunits (S20 and L26), [dubious – discuss] L7 and L12 are acetylated and methylated forms of the same protein, and L8 is a complex of L7/L12 and L10. In addition, L31 is known to exist in two forms, the full length at 7.9 kilodaltons (kDa) and fragmented at 7.0 kDa.
27367 Ensembl ENSG00000100316 ENSMUSG00000060036 UniProt P39023 P27659 RefSeq (mRNA) NM_001033853 NM_000967 NM_013762 RefSeq (protein) NP_000958 NP_001029025 NP_038790 Location (UCSC) Chr 22: 39.31 – 39.32 Mb Chr 15: 79.96 – 79.98 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse 60S ribosomal protein L3 is a protein that in humans is encoded by the RPL3 gene. Function Ribosomes ...
Ribosomes are the macromolecular machines that are responsible for mRNA translation into proteins. The eukaryotic ribosome, also called the 80S ribosome, is made up of two subunits – the large 60S subunit (which contains the 25S [in plants] or 28S [in mammals], 5.8S, and 5S rRNA and 46 ribosomal proteins) and a small 40S subunit (which contains the 18S rRNA and 33 ribosomal proteins). [6]
67025 Ensembl ENSG00000142676 ENSMUSG00000059291 UniProt P62913 Q5VVD0 Q9CXW4 RefSeq (mRNA) NM_001199802 NM_000975 NM_025919 RefSeq (protein) NP_000966 NP_001186731 NP_000966.2 NP_080195 Location (UCSC) Chr 1: 23.69 – 23.7 Mb Chr 4: 135.76 – 135.78 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse 60S ribosomal protein L11 is a protein that in humans is encoded by the RPL11 gene ...
Increased uterine NK cells: Natural killer cells, a type of white blood cell, are present in uterine tissue. High levels of these cells may be linked to RPL but high numbers or the presence of these cells is not a predictor of pregnancy loss in women who have not have had a miscarriage. [38]
A diagram showing mtDNA (circular) and mitochondrial ribosomes among other mitochondria structures. The mitochondrial ribosome, or mitoribosome, is a protein complex that is active in mitochondria and functions as a riboprotein for translating mitochondrial mRNAs encoded in mtDNA.
68028 Ensembl ENSG00000163584 ENSMUSG00000039221 UniProt Q6P5R6 Q9D7S7 RefSeq (mRNA) NM_001099645 NM_001320451 NM_026517 NM_001347226 RefSeq (protein) NP_001093115 NP_001307380 NP_001334155 NP_080793 Location (UCSC) Chr 3: 170.86 – 170.87 Mb Chr 3: 28.86 – 28.86 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Ribosomal protein L22 like 1 (RPL22L1), or eL22L1, is a protein that in ...
An example of this is the expression of AMPK in various cancers; its activation triggers a cascade that can ultimately allow the cancer to escape apoptosis (programmed cell death) triggered by nutrition deprivation. Future cancer therapies may involve disrupting the translation machinery of the cell to counter the downstream effects of cancer. [23]