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  2. Superficial siderosis - Wikipedia

    en.wikipedia.org/wiki/Superficial_siderosis

    Iron deposition is prevalent in siderotic brain tissues, with iron concentrations of 1.79 to 8.26 times normal levels. Ferritin , an iron storage protein, is over-produced in response to excess heme by glial cells in order to sequester iron, with production ranging from 20.1 to 27.4 times normal levels.

  3. Neuroferritinopathy - Wikipedia

    en.wikipedia.org/wiki/Neuroferritinopathy

    However this is unreliable as method of diagnosis since some patients show typical serum ferritin levels even at the latest stages of neuroferritinopathy. [1] Cerebral spinal fluid tests also are typically normal. [8] Ferritin aggregates found in the skin, liver, kidney and muscle tissues may help in diagnosing neuroferritinopathy. [8]

  4. Cerebral edema - Wikipedia

    en.wikipedia.org/wiki/Cerebral_edema

    Cerebral edema is a potentially life-threatening complication of severely decreased sodium ion concentration in the blood (hyponatremia). [17] Ionic brain edema can also occur around the sites of brain hemorrhages, infarcts, or contusions due to a local plasma osmolality pressure gradient when compared to the high osmolality in the affected tissue.

  5. Intracranial pressure - Wikipedia

    en.wikipedia.org/wiki/Intracranial_pressure

    An increase in pressure, most commonly due to head injury leading to intracranial hematoma or cerebral edema, can crush brain tissue, shift brain structures, contribute to hydrocephalus, cause brain herniation, and restrict blood supply to the brain. [13] It is a cause of reflex bradycardia. [14]

  6. Ferritin - Wikipedia

    en.wikipedia.org/wiki/Ferritin

    Serum ferritin levels are measured in medical laboratories as part of the iron studies workup for iron-deficiency anemia. [6] They are measured in nanograms per milliliter (ng/mL) or micrograms per liter (μg/L); the two units are equivalent. The ferritin levels measured usually have a direct correlation with the total amount of iron stored in ...

  7. Posterior reversible encephalopathy syndrome - Wikipedia

    en.wikipedia.org/wiki/Posterior_reversible...

    The excessive pressure damages the endothelial layer and the blood–brain barrier, leading to swelling (edema). The predilection toward the posterior brain may be explained by the reduced density of sympathetic innervation in the posterior circulation compared to the anterior circulation (thus a reduced adaptive capacity to fluctuations or ...

  8. Kidney specialists float a new theory after revisiting Bruce ...

    www.aol.com/news/kidney-specialists-float-theory...

    Lee's death was officially ruled the result of cerebral edemaswelling of the brain. While a normal human brain is about 3 pounds, Lee's was reportedly closer to 3½ pounds.

  9. Cerebrospinal fluid leak - Wikipedia

    en.wikipedia.org/wiki/Cerebrospinal_fluid_leak

    Cerebrospinal fluid is produced by the choroid plexus in the ventricles of the brain and contained by the dura and arachnoid layers of the meninges. [23] [42] [64] The brain floats in CSF, which also transports nutrients to the brain and spinal cord. As holes form in the spinal dura mater, CSF leaks out into the surrounding space.