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  2. Epithelial polarity - Wikipedia

    en.wikipedia.org/wiki/Epithelial_polarity

    Epithelial polarity is one example of the cell polarity that is a fundamental feature of many types of cells. Epithelial cells feature distinct 'apical', 'lateral' and 'basal' plasma membrane domains. Epithelial cells connect to one another via their lateral membranes to form epithelial sheets that line cavities and surfaces throughout the ...

  3. Cell polarity - Wikipedia

    en.wikipedia.org/wiki/Cell_polarity

    Epithelial cells also exhibit planar cell polarity, in which specialized structures are orientated within the plane of the epithelial sheet. Some examples of planar cell polarity include the scales of fish being oriented in the same direction and similarly the feathers of birds, the fur of mammals, and the cuticular projections (sensory hairs ...

  4. Madin-Darby canine kidney cells - Wikipedia

    en.wikipedia.org/wiki/Madin-Darby_Canine_Kidney...

    This work established that MDCK cells do not lose contacts with neighbors during the onset of branching morphogenesis, but that canonical markers of cell polarity are transiently lost. One outcome of this shift in polarity is the reorientation of cell division along a newly growing branch of cells, in order to correctly position daughter cells ...

  5. Sonic hedgehog protein - Wikipedia

    en.wikipedia.org/wiki/Sonic_hedgehog_protein

    6469 20423 Ensembl ENSG00000164690 ENSMUSG00000002633 UniProt Q15465 Q62226 RefSeq (mRNA) NM_000193 NM_001310462 NM_009170 RefSeq (protein) NP_000184 NP_001297391 NP_033196 Location (UCSC) Chr 7: 155.8 – 155.81 Mb Chr 5: 28.66 – 28.67 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Sonic hedgehog protein (SHH) is a major signaling molecule of embryonic development in humans and ...

  6. Apical ectodermal ridge - Wikipedia

    en.wikipedia.org/wiki/Apical_ectodermal_ridge

    Between E10.5-11, a linear and compact AER with a polystratified epithelial structure (3-4 layers) has formed and positioned itself at the distal dorso-ventral boundary of the bud. [ 6 ] [ 8 ] [ 9 ] [ 10 ] After reaching its maximum height, the AER in mouse limb buds flattens and eventually become indistinguishable from the dorsal and ventral ...

  7. Neural crest - Wikipedia

    en.wikipedia.org/wiki/Neural_crest

    The neural crest is a ridge-like structure that is formed transiently between the epidermal ectoderm and neural plate during vertebrate development. Neural crest cells originate from this structure through the epithelial-mesenchymal transition, and in turn give rise to a diverse cell lineage—including melanocytes, craniofacial cartilage and bone, smooth muscle, dentin, peripheral and enteric ...

  8. Planar cell polarity - Wikipedia

    en.wikipedia.org/wiki/Planar_cell_polarity

    Planar cell polarity (PCP) is the protein-mediated signaling that coordinates the orientation of cells in a layer of epithelial tissue. In vertebrates, examples of mature PCP oriented tissue are the stereo-cilia bundles in the inner ear, [ 1 ] motile cilia of the epithelium, [ 2 ] and cell motility in epidermal wound healing. [ 3 ]

  9. Lewis' law - Wikipedia

    en.wikipedia.org/wiki/Lewis'_law

    A variety of empirical studies in different epithelial tissues have confirmed Lewis' law. [3] [4] [5]It has been suggested [6] that the emergence of Lewis' law on the apical surface of epithelia is a result of the concurrence of