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  2. Epithelial polarity - Wikipedia

    en.wikipedia.org/wiki/Epithelial_polarity

    Epithelial polarity is one example of the cell polarity that is a fundamental feature of many types of cells. Epithelial cells feature distinct 'apical', 'lateral' and 'basal' plasma membrane domains. Epithelial cells connect to one another via their lateral membranes to form epithelial sheets that line cavities and surfaces throughout the ...

  3. Madin-Darby canine kidney cells - Wikipedia

    en.wikipedia.org/wiki/Madin-Darby_Canine_Kidney...

    This work established that MDCK cells do not lose contacts with neighbors during the onset of branching morphogenesis, but that canonical markers of cell polarity are transiently lost. One outcome of this shift in polarity is the reorientation of cell division along a newly growing branch of cells, in order to correctly position daughter cells ...

  4. Cell polarity - Wikipedia

    en.wikipedia.org/wiki/Cell_polarity

    Epithelial cells also exhibit planar cell polarity, in which specialized structures are orientated within the plane of the epithelial sheet. Some examples of planar cell polarity include the scales of fish being oriented in the same direction and similarly the feathers of birds, the fur of mammals, and the cuticular projections (sensory hairs ...

  5. Planar cell polarity - Wikipedia

    en.wikipedia.org/wiki/Planar_cell_polarity

    Planar cell polarity (PCP) is the protein-mediated signaling that coordinates the orientation of cells in a layer of epithelial tissue. In vertebrates, examples of mature PCP oriented tissue are the stereo-cilia bundles in the inner ear, [ 1 ] motile cilia of the epithelium, [ 2 ] and cell motility in epidermal wound healing. [ 3 ]

  6. Developmental biology - Wikipedia

    en.wikipedia.org/wiki/Developmental_biology

    Morphogenesis is important for creating the three germ layers of the early embryo (ectoderm, mesoderm, and endoderm) and for building up complex structures during organ development. Tissue growth involves both an overall increase in tissue size, and also the differential growth of parts ( allometry ) which contributes to morphogenesis.

  7. Apical ectodermal ridge - Wikipedia

    en.wikipedia.org/wiki/Apical_ectodermal_ridge

    Between E10.5-11, a linear and compact AER with a polystratified epithelial structure (3-4 layers) has formed and positioned itself at the distal dorso-ventral boundary of the bud. [ 6 ] [ 8 ] [ 9 ] [ 10 ] After reaching its maximum height, the AER in mouse limb buds flattens and eventually become indistinguishable from the dorsal and ventral ...

  8. Neuroepithelial cell - Wikipedia

    en.wikipedia.org/wiki/Neuroepithelial_cell

    The neural tube begins as a single layer of pseudostratified epithelial cells, but rapid proliferation of neuroepithelial cells creates additional layers and eventually three distinct regions of growth. [2] [4] As these additional layers form the apical-basal polarity must be downregulated. [3]

  9. Apical constriction - Wikipedia

    en.wikipedia.org/wiki/Apical_constriction

    In morphogenesis, apical constriction is the process in which contraction of the apical side of a cell causes the cell to take on a wedged shape. Generally, this shape change is coordinated across many cells of an epithelial layer, generating forces that can bend or fold the cell sheet.