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However, some research has suggested that the symptoms of hysteroid dysphoria manifest differently across men and women. [18] The degree of rejection sensitivity in participants was measured using a ‘rejection sensitive questionnaire’ and attitudes towards intimacy were identified using a ‘fear of intimacy scale’.
A more recent (1996) definition of rejection sensitivity is the tendency to "anxiously expect, readily perceive, and overreact" to social rejection. [54] People differ in their readiness to perceive and react to rejection. [54] The causes of individual differences in rejection sensitivity are not well understood.
Symptoms: Low mood, mood reactivity, hyperphagia, hypersomnia, leaden paralysis, interpersonal rejection sensitivity: Complications: Self-harm: Usual onset: Typically adolescence [1] Types: Primary anxious, primarily vegetative [1] Risk factors: Bipolar disorder, anxiety disorder, female sex [2] Differential diagnosis
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One may treat underlying causes such as depression (especially dysthymia or major depressive disorder) or bipolar disorder as well as the dysphoric symptoms themselves. [ citation needed ] The 11th revision of the International Classification of Diseases (ICD-11) defines dysphoria as "an unpleasant mood state, which can include feelings of ...
Bradycardia; Hypertension (high blood pressure); Allergic reactions (e.g. dyspnoea (shortness of breath), bronchospasm, wheezing, angioneurotic oedema) Anaphylaxis; Changes in appetite
Intolerance to analgesics, particularly NSAIDs, is relatively common. It is thought that a variation in the metabolism of arachidonic acid is responsible for the intolerance. Symptoms include chronic rhinosinusitis with nasal polyps, asthma, gastrointestinal ulcers, angioedema, and urticaria. [3]
For many biologics (e.g., monoclonal antibodies), injection site reactions are the most common adverse effect of the drug, and have been reported to have an incidence rate of 0.5–40%. [2] In trials of subcutaneous administration of oligonucleotides, between 22 and 100% of subjects developed reactions depending on the oligonucleotide. [6]