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Z583 (GLXC-26150) is a chemical compound which acts as a potent and highly selective inhibitor of JAK3, and was developed for the treatment of rheumatoid arthritis ...
The organisation has its origins in 1911, with the passing of the Public Debt Commissioners Act of 1911, a year after the formation of the Union of South Africa. [4]: 3 Known then as the Public Debt Commissioners, it would manage the government's debt, investing the government and South African Railways and Harbours trust funds and by 1924 had taken on the provincial administrators funds as well.
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