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The metabolism of metoprolol can vary widely among patients, often as a result of hepatic impairment [9] or CYP2D6 polymorphism. [10] Metoprolol was first made in 1969, patented in 1970, and approved for medical use in 1978. [11] [12] [13] It is on the World Health Organization's List of Essential Medicines. [14] It is available as a generic ...
Civica Rx is a nonprofit generic drug company founded in 2018 by leading U.S. health systems and philanthropies [1] for the purpose of preventing and mitigating drug shortages in the United States, and the price hikes that can accompany them. [2] Civica's mission is to make quality generic medicines accessible and affordable to everyone.
It specializes in the field of authorized generics, generic drugs manufactured by the branded innovator company but marketed under a private label. According to IMS Health , the pharmaceutical industry auditing service, Prasco is one of the fastest growing pharmaceutical companies in the industry, in terms of relative growth and prescriptions ...
In 2018, Amneal Pharmaceuticals LLC merged with Impax Laboratories, Inc. to form Amneal Pharmaceuticals, Inc. The FTC described the merger as having a value of US$1.45 billion, and required the companies to divest several marketed products and development projects as a condition of the approval. [16]
In 2011 and 2012, GPhA and the U.S. Food and Drug Administration negotiated the Generic Drug User Fee Act (GDUFA), which requires manufacturers of generic prescription drugs to pay application fees when submitting Abbreviated New Drug Applications (ANDAs) seeking approval for generic products. [10]
2010: Endo acquired generic manufacturer Qualitest Pharmaceuticals for $1.2 billion [8] 2011: Endo acquired medical device manufacturer American Medical Systems for more than $2 billion [18] [19] [7] 2013: Endo agreed to purchase Paladin Labs Inc for about $1.6 billion to gain access to the Canadian market as well as expand into emerging markets.
Brand names and generic names are differentiated by capitalizing brand names. See also the list of the top 100 bestselling branded drugs, ranked by sales. Abbreviations are used in the list as follows: INN = International nonproprietary name; BAN = British Approved Name; USAN = United States Adopted Name; Two-letter codes for countries
By 2023, Apotex employed close to 8,000 people as Canada's largest drug manufacturer, with over 300 products selling in over 115 countries. [2] [6] [7] Apotex manufactures and distributes generic medications for a range of diseases and health conditions that include cancer, diabetes, high cholesterol, glaucoma, infections and blood pressure.