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A high-resolution spectral-domain OCT scan (3×3 mm) of a dry age-related macular degeneration eye showing geographic atrophy and drusen in macula on both cross-sectional and en face fly-through. Optical coherence tomography ( OCT ) is a high-resolution imaging technique with most of its applications in medicine and biology.
[18] [19] This has allowed OCTA to obtain detailed images of retinal vasculature in the human retina [20] and become widely used clinically to diagnose a variety of eye diseases, such as age related macular degeneration (AMD), [21] diabetic retinopathy (DR), [22] [23] artery and vein occlusions, and glaucoma. [24] [18]
Fundus photographs are also used to document abnormalities of disease process affecting the eye, and/or to follow up on the progress of the eye condition/disease such as diabetes, age-macular degeneration (AMD), glaucoma, multiple sclerosis, and neoplasm of the choroid, cranial nerves, retinal or eyeball.
The incidence of age-related macular degeneration and its associated features increases with age and is low in people <55 years of age. [101] Smoking is the strongest modifiable risk factor. [102] As of 2008, age-related macular degeneration accounts for more than 54% of all vision loss in the white population in the US. [103]
The diagnosis usually starts with a dilated examination of the retina, followed with confirmation by optical coherence tomography, fluorescein angiography, and indocyanine green angiography. The angiography test will usually show one or more fluorescent spots with fluid leakage. In 10%-15% of the cases these will appear in a classic smokestack ...
Fundus of geographic atrophy. Geographic atrophy (GA), also known as atrophic age-related macular degeneration (AMD) or advanced dry AMD, is an advanced form of age-related macular degeneration that can result in the progressive and irreversible loss of retinal tissue (photoreceptors, retinal pigment epithelium, choriocapillaris) which can lead to a loss of central vision over time.
Scanning laser ophthalmoscopy developed as a method to view a distinct layer of the living eye at the microscopic level. The use of confocal methods to diminish extra light by focusing detected light through a small pinhole made possible the imaging of individual layers of the retina with greater distinction than ever before. [4]
Optical coherence tomography scans of the orbits or head, calcification at the head of the optic nerve without change in size of globe strongly suggests drusen in a middle-age or elderly patient. Whether drusen promote AMD or are symptomatic of an underlying process that causes both drusen and AMD is not known, but they are indicators of ...
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