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  2. N-Hydroxysuccinimide - Wikipedia

    en.wikipedia.org/wiki/N-Hydroxysuccinimide

    N-Hydroxysuccinimide (NHS) is an organic compound with the formula (CH 2 CO) 2 NOH. It is a white solid that is used as a reagent for preparing active esters in peptide synthesis. It can be synthesized by heating succinic anhydride with hydroxylamine or hydroxylamine hydrochloride. [2]

  3. Disuccinimidyl suberate - Wikipedia

    en.wikipedia.org/wiki/Disuccinimidyl_suberate

    It consists of functional groups It is a homobifunctional N-hydroxysuccinimide (NHS) ester formed by carbodiimide-activation of carboxylate molecules, with identical reactive groups at either end. [2] The reactive groups are separated by a spacer and in this molecule it is a six carbon alkyl chain. [3]

  4. Active ester - Wikipedia

    en.wikipedia.org/wiki/Active_ester

    Active esters are often used in peptide synthesis, e.g., N-hydroxysuccinimide, hydroxybenzotriazole. [1] Active esters of acrylic acid are precursors to polymers with reactive side chains. [4] The concept of active esters extends to esters of phosphoric and sulfuric acids. One such case is dimethylsulfate, a strong methylating agent.

  5. Bissulfosuccinimidyl suberate - Wikipedia

    en.wikipedia.org/wiki/BisSulfosuccinimidyl_suberate

    Amine reactive: BS3 is amine-reactive in that its N-hydroxysulfosuccinimide (NHS) esters at each end react specifically with primary amines to form stable amide bonds in a nucleophilic acyl substitution-type reaction in which the N-hydroxysulfosuccinimide acts as the leaving group. [9]

  6. Biotinylation - Wikipedia

    en.wikipedia.org/wiki/Biotinylation

    The water solubility of sulfo-NHS-esters stems from their sulfonate group on the N-hydroxysuccinimide ring and eliminates the need to dissolve the reagent in an organic solvent. Sulfo-NHS-esters of biotin also can be used as cell surface biotinylation reagents, because they do not penetrate the cell membrane.

  7. 3 Rare Nickels Worth Big Money in 2025 - AOL

    www.aol.com/3-rare-nickels-worth-big-110133203.html

    With the penny potentially about to become extinct as a result of President Donald Trump's guidance to the Treasury Department to stop production of the one-cent coin, attention may perhaps soon ...

  8. N-Hydroxyphthalimide - Wikipedia

    en.wikipedia.org/wiki/N-Hydroxyphthalimide

    Nefkens and Tesser developed a technique for generating active esters from N-hydroxyphthalimide [14] for use in peptide synthesis, [15] an approach later extended to using N-hydroxysuccinimide. [16] The ester linkage is formed between the N-hydroxyphthalimide and a carboxylic acid by elimination of water, the coupling achieved with N,N ...

  9. The 6 Best Frozen Foods for Cognitive Health, According to ...

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    Carolina Schneider, M.S., RD, a Brooklyn, N.Y.-based dietitian, is a big fan of frozen leafy greens like spinach and kale. “Leafy greens are packed with vitamin K, which supports memory and ...

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