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A mitogen-activated protein kinase (MAPK or MAP kinase) is a type of serine/threonine-specific protein kinases involved in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines.
Its sources are located in the Adula Alps (Rheinwaldhorn, Rheinquellhorn, and Güferhorn). The Avers Rhine joins from the south. One of its headwaters, the Reno di Lei (stowed in the Lago di Lei), is partially located in Italy. Near Sils the Posterior Rhine is joined by the Albula, from the east, from the Albula Pass region.
South Asia is the southern subregion of Asia, which is defined in both geographical and ethnic-cultural terms. With a population of 2.04 billion living in South Asia, it contains a quarter (25%) of the world's population.
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[4] [5] The reef is located in the Coral Sea, off the coast of Queensland, Australia, separated from the coast by a channel 160 kilometres (100 mi) wide in places and over 61 metres (200 ft) deep. [6] The Great Barrier Reef can be seen from outer space and is the world's biggest single structure made by living organisms. [7]
The MiG-21 jet fighter was a continuation of Soviet jet fighters, starting with the subsonic MiG-15 and MiG-17, and the supersonic MiG-19.A number of experimental Mach 2 Soviet designs were based on nose intakes with either swept-back wings, such as the Sukhoi Su-7, or tailed deltas, of which the MiG-21 would be the most successful.
New York, also called New York State, [b] is a state in the Northeastern United States, bordering the Atlantic Ocean, New England, Canada, and the Great Lakes. [c] With approximately 20 million residents, [8] it is the fourth-most populous state in the United States, and the 27th-largest state by area, with a total area of 54,556 square miles (141,300 km 2).