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Coagulation, also known as clotting, is the process by which blood changes from a liquid to a gel, forming a blood clot. It results in hemostasis , the cessation of blood loss from a damaged vessel, followed by repair.
The trauma triad of death is a medical term describing the combination of hypothermia, acidosis, and coagulopathy. [1] This combination is commonly seen in patients who have sustained severe traumatic injuries and results in a significant rise in the mortality rate . [ 2 ]
Hypovolemia is a massive decrease in blood volume, and death by excessive loss of blood is referred to as exsanguination. [2] Typically, a healthy person can endure a loss of 10–15% of the total blood volume without serious medical difficulties (by comparison, blood donation typically takes 8–10% of the donor's blood volume). [3]
In a small blood vessel, blood flow may be completely cut off (termed an occlusive thrombus), resulting in death of tissue supplied by that vessel. If a thrombus dislodges and becomes free-floating, it is considered an embolus. [citation needed] If an embolus becomes trapped within a blood vessel, it blocks blood flow and is termed as an ...
Thrombosis (from Ancient Greek θρόμβωσις (thrómbōsis) 'clotting') is the formation of a blood clot inside a blood vessel, obstructing the flow of blood through the circulatory system. When a blood vessel (a vein or an artery) is injured, the body uses platelets (thrombocytes) and fibrin to form a blood clot to prevent blood loss ...
The blood clot contains the secondary hemostasis plug with blood cells trapped in it. This is a necessary step for wound healing , but it has the ability to cause severe health problems if the thrombus becomes detached from the vessel wall and travels through the circulatory system; If it reaches the brain, heart or lungs it could lead to ...
Blood typically exits the wound in spurts, rather than in a steady flow; the blood spurts out in time with the heartbeat. The amount of blood loss can be copious, and can occur very rapidly. [10] Venous bleeding: This blood is flowing from a damaged vein. As a result, it is blackish in colour (due to the lack of oxygen it transports) and flows ...
Thromboembolism is a condition in which a blood clot breaks off from its original site and travels through the bloodstream (as an embolus) to obstruct a blood vessel, causing tissue ischemia and organ damage. Thromboembolism can affect both the venous and arterial systems, with different clinical manifestations and management strategies.