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Rhabdomyolysis (shortened as rhabdo) is a condition in which damaged skeletal muscle breaks down rapidly, often due to high intensity exercise over a short period. [ 6 ] [ 4 ] [ 5 ] Symptoms may include muscle pains , weakness, vomiting , and confusion .
Exertional rhabdomyolysis, the exercise-induced muscle breakdown that results in muscle pain/soreness, is commonly diagnosed using the urine myoglobin test accompanied by high levels of creatine kinase (CK). Myoglobin is the protein released into the bloodstream when skeletal muscle is broken down. The urine test simply examines whether ...
Osteoporosis, including drug- and cancer-related osteoporosis, giant cell tumour of bone and hypercalcaemia of malignancies: Hypercholesterolaemia, cataract, urinary retention, hypocalcaemia, osteonecrosis of the jaw and anaphylaxis. Gemtuzumab ozogamicin: IV: CD33 antibody that induces apoptosis of the tagged cell. Acute myeloid leukaemia
Rhabdomyolysis (rapid breakdown of damaged or injured skeletal muscle) Elevated creatine kinase levels Dry, thinning skin and decreased production of sebum (an oily substance that products your skin)
A strenuous offseason workout on Jan. 6 sent multiple Rockwall-Heath athletes to the hospital with rhabdomyolysis. Here’s what the symptoms look like. ... Early treatment can prevent serious ...
An example is: when a person taking a cholesterol-lowering statin drug then drinking grapefruit juice, they may have a poor treatment outcome (adverse drug reaction) and sustain liver damage or kidney failure due to drug induced rhabdomyolysis (the breaking up of muscle tissue). [7]
Statin-induced rhabdomyolysis is rare, occurring in less than 0.1% of people who take statins. [ 64 ] [ 65 ] [ 66 ] Statin induced rhabdomyolysis, as with other statin associated muscle symptoms, occurs most commonly in the first year of treatment but can occur at any time during treatment. [ 64 ]
Myoglobinuria is the presence of myoglobin in the urine, which usually results from rhabdomyolysis or muscle injury. [1] Myoglobin is present in muscle cells as a reserve of oxygen . Signs and symptoms