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The overall prevalence increases with age, with the largest increase in people over 65 years of age. [3] The prevalence of diabetes in America is estimated to increase to 48.3 million by 2050. [3] Diabetes mellitus occurs throughout the world, but is more common (especially type 2) in the more developed countries.
Obesity has been found to contribute to approximately 55% of cases of type 2 diabetes; [10] chronic obesity leads to increased insulin resistance that can develop into type 2 diabetes, [11] most likely because adipose tissue (especially that in the abdomen around internal organs) is a source of several chemical signals, hormones and cytokines, to other tissues.
As of 2011 more than 36 genes have been found that contribute to the risk of type 2 diabetes. [2] All of these genes together still only account for 10% of the total genetic component of the disease. [2] There are a number of rare cases of diabetes that arise due to an abnormality in a single gene (known as monogenic forms of diabetes). [1]
This is an accepted version of this page This is the latest accepted revision, reviewed on 17 December 2024. Group of endocrine diseases characterized by high blood sugar levels This article is about the common insulin disorder. For the urine hyper-production disorder, see Diabetes insipidus. For other uses, see Diabetes (disambiguation). Medical condition Diabetes mellitus Universal blue ...
Countless Americans have pre-diabetes or diabetes and, like Blue was, are oblivious. More than 80% of those who have prediabetes aren’t aware of it, according to the U.S. Centers for Disease ...
There are expected to be 11 million more obese adults in the UK by 2030, accruing up to 668,000 additional cases of diabetes mellitus, 461,000 cases of heart disease and stroke, 130,000 cases of cancer, with associated medical costs set to increase by £1.9–2.0B per year by 2030. [5] Adult obesity rates have almost quadrupled in the last 25 ...
Type 2 diabetes More than 53,000 people in the U.S. will die from colorectal cancer this year, the ACS estimates. It’s the third-leading cause of cancer-related deaths in men, fourth in women ...
In the UK, the NHS's diabetes prevention programme Healthier You offers personalised face-to-face and digital services. [26] Assessment of the programme is ongoing, but based on the first 36,000 patients, it seems that those who complete the programme manage to reduce their blood sugar levels and lose weight.