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Aromatic amines are chemicals that are produced when products such as dyes, polyurethane products, and certain pesticides are made. They are also found in cigarette smoke, fuel exhaust, and in overcooked, burned meat. The three types of aromatic amines, monocyclic, polycyclic, and heterocyclic, have all been found in recent studies of breast ...
Ames test procedure. The Ames test is a widely employed method that uses bacteria to test whether a given chemical can cause mutations in the DNA of the test organism. More formally, it is a biological assay to assess the mutagenic potential of chemical compounds. [1]
Having a super-sensitive multi-cancer screening tool that could actually save lives is the “holy grail” for cancer researchers and physicians. The aptly named health care company Grail claims ...
These are also known as "indirect-acting" carcinogens. Examples of activation-dependent carcinogens include polycyclic aromatic hydrocarbons (PAHs), heterocyclic aromatic amines, and mycotoxins. Activation-independent carcinogens, or "direct-acting" carcinogens, are those that are capable of directly damaging DNA without any modification to ...
The consequences of overdiagnosis and overtreatment resulting from cancer screening can lead to a decline in quality of life, due to the adverse effects of unnecessary medication and hospitalization. [10] [12] [13] The accuracy of a cancer screening test relies on its sensitivity, and low sensitivity screening tests can overlook cancers. [10]
4,4′-Methylenebis(2-chloroaniline) (also known as MOCA, MBOCA, and bisamine) is a substance used as a curing agent in polyurethane production. [3] MOCA is an aromatic amine which is structurally similar to benzidine, a known human bladder carcinogen.
In organic chemistry, an aromatic amine is an organic compound consisting of an aromatic ring attached to an amine. It is a broad class of compounds that encompasses anilines , but also many more complex aromatic rings and many amine substituents beyond NH 2 .
As with some other aromatic amines such as 2-naphthylamine, benzidine has been significantly withdrawn from use in most industries because it is so carcinogenic. In August 2010 benzidine dyes were included in the U.S. EPA's List of Chemicals of Concern. [ 7 ]