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Ventilator-associated pneumonia (VAP) is a type of lung infection that occurs in people who are on mechanical ventilation breathing machines in hospitals. As such, VAP typically affects critically ill persons that are in an intensive care unit (ICU) and have been on a mechanical ventilator for at least 48 hours.
Hypoxic ventilatory response (HVR) is the increase in ventilation induced by hypoxia that allows the body to take in and transport lower concentrations of oxygen at higher rates. It is initially elevated in lowlanders who travel to high altitude, but reduces significantly over time as people acclimatize .
High frequency ventilation is thought to reduce ventilator-associated lung injury, especially in the context of ARDS and acute lung injury. [ 7 ] Permissive hypercapnia and hypoxaemia allow the patient to be ventilated at less aggressive settings and can, therefore, mitigate all forms of ventilator-associated lung injury
Tachypnea, also spelt tachypnoea, is a respiratory rate greater than normal, resulting in abnormally rapid and shallow breathing. [1]In adult humans at rest, any respiratory rate of 12–20 per minute is considered clinically normal, with tachypnea being any rate above that. [2]
The IPI is a patient index which provides a simple indication in real time of the patient's overall ventilatory status as an integer ranging from numbers 1 to 10. IPI integrates four major physiological parameters provided by a patient monitor, using this information along with an algorithm to produce the IPI score.
Applied PEEP is usually one of the first ventilator settings chosen when mechanical ventilation is initiated. It is set directly on the ventilator.. A small amount of applied PEEP (4 to 5 cmH 2 O) is used in most mechanically ventilated patients to mitigate end-expiratory alveolar collapse. [6]
Signs and symptoms may include shortness of breath, fast breathing, and a low oxygen level in the blood due to abnormal ventilation. [ 7 ] [ 8 ] Other common symptoms include muscle fatigue and general weakness, low blood pressure, a dry, hacking cough, and fever.
Factors that may induce or sustain [2] hyperventilation include: physiological stress, anxiety or panic disorder, high altitude, head injury, stroke, respiratory disorders such as asthma, pneumonia, or hyperventilation syndrome, [5] cardiovascular problems such as pulmonary embolisms, anemia, an incorrectly calibrated medical respirator, [1] [3 ...