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Biguanide (/ b aɪ ˈ ɡ w ɒ n aɪ d /) is the organic compound with the formula HN(C(NH)NH 2) 2. It is a colorless solid that dissolves in water to give a highly basic solution. It is a colorless solid that dissolves in water to give a highly basic solution.
Print/export Download as PDF; Printable version; In other projects ... Pages in category "Biguanides" The following 18 pages are in this category, out of 18 total.
Phenformin is an antidiabetic drug from the biguanide class. It was marketed as DBI by Ciba-Geigy, but was withdrawn from most markets in the late 1970s due to a high risk of lactic acidosis, which was fatal in 50% of cases. Phenformin was developed in 1957 by Ungar, Freedman and Seymour Shapiro, working for the U.S. Vitamin Corporation ...
Structure of chlorhexidine, a bisbiguanide antiseptic.. Bisbiguanides are a class of chemically related compounds known for their bactericidal properties. Generally considered to be of the generic formula: R 1 R 2 N.C(:NR 6)NH.C(:NH)NH.CH 2 X--(CH 2) 3 NH.C(:NH)NH.C(:NR 7)NR 3 R 4 V. [1] These compounds include the antiseptics chlorhexidine and alexidine.
The lactic acidosis occurred only in patients with a buformin plasma level of greater than 0.60 μg/mL and was rare in patients with normal renal function. [19] [20] [21] In one report, the toxic oral dose was 329 ± 30 mg/day in 24 patients who developed lactic acidosis on buformin.
Legal experts believe the unknown female celebrity tied to the Jay-Z and Sean "Diddy" Combs rape lawsuit has sought her own representation with attorneys.
Megan Liu, lead study author and science and policy manager at Toxic-Free Future, tells Yahoo Life that this was a “minor point” in the study. “We feel bad that this happened,” she adds.
The researchers analyzed historical data on childhood blood-lead levels, leaded gas use and U.S. population statistics, determining that more than 170 million Americans had "clinically concerning ...