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An experimental design or randomized clinical trial requires careful consideration of several factors before actually doing the experiment. [33] An experimental design is the laying out of a detailed experimental plan in advance of doing the experiment.
Factorial designs allow the effects of a factor to be estimated at several levels of the other factors, yielding conclusions that are valid over a range of experimental conditions. The main disadvantage of the full factorial design is its sample size requirement, which grows exponentially with the number of factors or inputs considered. [6]
The second type is comparative research. These designs compare two or more groups on one or more variable, such as the effect of gender on grades. The third type of non-experimental research is a longitudinal design. A longitudinal design examines variables such as performance exhibited by a group or groups over time (see Longitudinal study).
This is a workable experimental design, but purely from the point of view of statistical accuracy (ignoring any other factors), a better design would be to give each person one regular sole and one new sole, randomly assigning the two types to the left and right shoe of each volunteer. Such a design is called a "randomized complete block design."
In the statistical theory of design of experiments, randomization involves randomly allocating the experimental units across the treatment groups.For example, if an experiment compares a new drug against a standard drug, then the patients should be allocated to either the new drug or to the standard drug control using randomization.
In the design of experiments, a between-group design is an experiment that has two or more groups of subjects each being tested by a different testing factor simultaneously. This design is usually used in place of, or in some cases in conjunction with, the within-subject design , which applies the same variations of conditions to each subject ...
An example of an unrandomized design would be to always run 2 replications for the first level, then 2 for the second level, and finally 2 for the third level. To randomize the runs, one way would be to put 6 slips of paper in a box with 2 having level 1, 2 having level 2, and 2 having level 3.
In the design of experiments, optimal experimental designs (or optimum designs [2]) are a class of experimental designs that are optimal with respect to some statistical criterion. The creation of this field of statistics has been credited to Danish statistician Kirstine Smith .