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Aromatase excess syndrome (AES or AEXS) is a rarely diagnosed genetic and endocrine syndrome which is characterized by an overexpression of aromatase, the enzyme responsible for the biosynthesis of the estrogen sex hormones from the androgens, in turn resulting in excessive levels of circulating estrogens and, accordingly, symptoms of hyperestrogenism.
Signs of hyperestrogenism may include heightened levels of one or more of the estrogen sex hormones (usually estradiol and/or estrone), lowered levels of follicle-stimulating hormone and/or luteinizing hormone (due to suppression of the hypothalamic–pituitary–gonadal axis by estrogen), and lowered levels of androgens such as testosterone (generally only relevant to males). [1]
Research on hot flashes is mostly focused on treatment options. The exact cause and pathogenesis, or causes, of vasomotor symptoms (VMS)—the clinical name for hot flashes—has not yet been fully studied. [11] [12] Hot flashes are associated with declining levels of estrogen (estrogen withdrawal) and other hormonal changes. [13]
E2 can protect the heart and individual cardiac myocytes from injuries related to ischemia. After a heart attack or long periods of hypertension, E2 inhibits the adverse effects of pathologic remodeling of the heart. [40] During pregnancy, high levels of estrogens, namely estradiol, increase coagulation and the risk of venous thromboembolism
Diabetes is very common. The Centers for Disease Control and Prevention (CDC) notes that 38.4 million people in the United States are currently living with diabetes. That’s 11.6 percent of the ...
Gynecomastia in older men is estimated to be present in 24–65 percent of men between the ages of 50 and 80. Estimates on asymptomatic gynecomastia is about up to 70% in men aged 50 to 69 years. [26] [50] The prevalence of gynecomastia in men may have increased in recent years, but the epidemiology of the disorder is not fully understood. [40]
The second was when I intermittently peed blood over a 10-month stint. ... as compared to men, and women are more likely to seek help for their anxiety symptoms. Therefore, men are more likely to ...
Prediabetes doesn’t come with many symptoms, so most people with the conadition — about 90 percent — don’t know they have it. If you do experience prediabetes symptoms , you may notice ...
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