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Pantoprazole, sold under the brand name Protonix, among others, is a medication used for the treatment of stomach ulcers, short-term treatment of erosive esophagitis due to gastroesophageal reflux disease (GERD), maintenance of healing of erosive esophagitis, and pathological hypersecretory conditions including Zollinger–Ellison syndrome.
[20] [21] [22] In the United States, the Food and Drug Administration (FDA) has advised that over-the-counter PPIs, such as Prilosec OTC, should be used no more than three 14-day treatment courses over one year. [23] [24] Despite their extensive use, the quality of the evidence supporting their use in some of these conditions is variable.
In pharmacokinetics, the rate of infusion (or dosing rate) refers not just to the rate at which a drug is administered, but the desired rate at which a drug should be administered to achieve a steady state of a fixed dose which has been demonstrated to be therapeutically effective. Abbreviations include K in, [1] K 0, [2] or R 0.
That could mean inviting friends over to check out the holiday light displays in your neighborhood (with mugs of hot chocolate at the ready) instead of hosting a cocktail party.
About 70% of pump enzyme is inhibited, as PPIs have a short half-life and not all pump enzymes are activated. It takes about 3 days to reach steady-state inhibition of acid secretion, as a balance is struck between covalent inhibition of active pumps, subsequent stimulation of inactive pumps after the drug has been eliminated from the blood ...
Josh Mankiewicz says he doesn’t flinch anymore watching himself on TV after dropping 70-lbs.. The Dateline correspondent, 69, opened up to PEOPLE about his impressive weight loss journey for the ...
President Joe Biden marked Jan. 9 as a national day of mourning in honor of the death of former President Jimmy Carter.
Heavy alcohol consumption over 2 weeks may decrease vitamin B12 absorption, which may reduce the effectiveness of this anti-ulcer agent. [14] Vitamin B12 may also interact with other medications. The therapeutic effect of this supplement may be reduced by chloramphenicol .