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Mucous cells of the stomach lining secrete mucus (pink) into the lumen. Mucus (/ ˈ m j uː k ə s /, MEW-kəs) is a slippery aqueous secretion produced by, and covering, mucous membranes. It is typically produced from cells found in mucous glands, although it may also originate from mixed glands, which contain both serous and mucous cells.
The mucosa is composed of one or more layers of epithelial cells that secrete mucus, and an underlying lamina propria of loose connective tissue. [1] The type of cells and type of mucus secreted vary from organ to organ and each can differ along a given tract. [2] [3]
The mucus produced by these cells is extremely important, as it prevents the stomach from digesting itself. [5] Parietal cells produce potent hydrochloric acid, which damages cells. Gastric chief cells produce pepsinogen, which is activated by the acid to form pepsin. Pepsin is a protease that can digest and damage stomach cells.
The excessive mucus production seen in allergic asthma patients is due to goblet cell metaplasia, the differentiation of airway epithelial cells into mucin producing goblet cells. [17] These cells produce the thick mucins MUC5AC and MUC5B , which clog the airway, leading to the airflow obstruction characteristic of asthma .
Another important cell type is the pulmonary neuroendocrine cell. These are innervated cells that only make up around 0.5% of the respiratory epithelial cells. [7] The ciliated cells are columnar epithelial cells with specialized ciliary modifications. The ciliated cells make up between 50 and 80 per cent of the epithelium. [8]
The ciliated part of the simple columnar epithelium has tiny hairs which help move mucus and other substances up the respiratory tract. The shape of the simple columnar epithelium cells are tall and narrow giving a column like appearance. the apical surfaces of the tissue face the lumen of organs while the basal side faces the basement membrane ...
These cells almost fill the tube and the remaining lumen is continued as a very fine channel. Cells found in the gastric glands include mucous neck cells, chief cells, parietal cells, G cells, and enterochromaffin-like cells (ECLs). The first cells of all of the glands are mucus-secreting foveolar cells that line the gastric pits.
They produce a glycoprotein, mucin that absorbs water to form a sticky secretion called mucus. They are from 12 to 25 mm. long, and about 8 mm. broad, and each opens by three or four ducts on the under surface of the apex. The Weber's glands are an example of muciparous glands located along the tongue.