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  2. Mass spectrometry - Wikipedia

    en.wikipedia.org/wiki/Mass_spectrometry

    Ion mobility spectrometry-mass spectrometry (IMS/MS or IMMS) is a technique where ions are first separated by drift time through some neutral gas under an applied electrical potential gradient before being introduced into a mass spectrometer. [43] Drift time is a measure of the collisional cross section relative to the charge of the ion.

  3. File:Mass Spectrometer Schematic.svg - Wikipedia

    en.wikipedia.org/wiki/File:Mass_Spectrometer...

    (Schematics of a typical en:mass spectrometer Public domain Public domain false false This image is in the public domain in the United States because it only contains materials that originally came from the United States Geological Survey , an agency of the United States Department of the Interior .

  4. Quadrupole mass analyzer - Wikipedia

    en.wikipedia.org/wiki/Quadrupole_mass_analyzer

    A mass-selecting quadrupole and collision quadrupole with time-of-flight device as the second mass selection stage is a hybrid known as a quadrupole time-of-flight mass spectrometer (QTOF MS). [ 8 ] [ 9 ] Quadrupole-quadrupole-time-of-flight (QqTOF) configurations are also possible and used especially the mass spectrometry of peptides and other ...

  5. Electron-capture dissociation - Wikipedia

    en.wikipedia.org/wiki/Electron-capture_dissociation

    Schematic diagram of the combined ECD FTICRMS and IRMPD experimental setup. Electron-capture dissociation (ECD) is a method of fragmenting gas-phase ions for structure elucidation of peptides and proteins in tandem mass spectrometry. It is one of the most widely used techniques for activation and dissociation of mass selected precursor ion in ...

  6. Mass chromatogram - Wikipedia

    en.wikipedia.org/wiki/Mass_chromatogram

    A mass chromatogram is a representation of mass spectrometry data as a chromatogram, where the x-axis represents time and the y-axis represents signal intensity. [1] The source data contains mass information; however, it is not graphically represented in a mass chromatogram in favor of visualizing signal intensity versus time.

  7. Gas chromatography–mass spectrometry - Wikipedia

    en.wikipedia.org/wiki/Gas_chromatography–mass...

    The first on-line coupling of gas chromatography to a mass spectrometer was reported in the late 1950s. [4] [5] An interest in coupling the methods had been suggested as early as December 1954, [6] but conventional recording techniques had too poor temporal resolution.

  8. Chemical ionization - Wikipedia

    en.wikipedia.org/wiki/Chemical_ionization

    A schematic diagram of chemical ionization source. Chemical ionization (CI) is a soft ionization technique used in mass spectrometry. [1] [2] This was first introduced by Burnaby Munson and Frank H. Field in 1966. [3] This technique is a branch of gaseous ion-molecule chemistry. [2]

  9. Triple quadrupole mass spectrometer - Wikipedia

    en.wikipedia.org/wiki/Triple_quadrupole_mass...

    Both, the first mass analyzer and the collision cell are continuously exposed to ions from the source, in a time independent manner. [4] It is once the ions move into the third mass analyzer that time dependence becomes a factor. [4] The first quadrupole mass filter, Q1, is the primary m/z selector after the sample leaves the ionization source.

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