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This breed of rat was first produced by the Sprague Dawley farms (later to become the Sprague Dawley Animal Company) in Madison, Wisconsin, in 1925. The name was originally hyphenated, although the brand styling today (Sprague Dawley, the trademark used by Inotiv) is not. The average litter size of the Sprague Dawley rat is 11.0. [29]
Sprague Dawley rat; W. Wistar rat; Z. ZDF rat; Zucker diabetic fatty rat; Zucker rat This page was last edited on 12 October 2015, at 22:02 (UTC). Text is available ...
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The company began offering rats in 1969, including Sprague Dawley, one of the most popular breeds of laboratory rats. That same year, Taconic became the first breeder to receive full accreditation from the American Association for the Accreditation of Laboratory Animals.
Phytol was found to cause pulmonary hemorrhage and necrosis of nose, throat and lung tissue when exposed in aerosol to Sprague Dawley rats, with no safe dose range being established. A majority of the phytol rats turned out dead or moribund, leading to 2nd-day termination of the 14-day study. [10]
Losing weight. If you’re overweight and not seeing results with exercise and diet alone, you may want to consider weight loss medication like glucagon-like peptide-1s (GLP-1s).
Harlan UK Ltd. is the British arm of Harlan Sprague Dawley Inc. It has an annual turnover of £6.6 million, according to the British Union for the Abolition of Vivisection (BUAV). [6] The company supplies marmosets, beagles, cats, rabbits, guinea pigs, rats, mice, gerbils, and hamsters, as well as hybrid, mutant, and transgenic animals.
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