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This includes studies on supplements containing glucosamine, chondroitin sulfate, and methylsulfonylmethane (MSM). [20] Because they are not regulated, joint supplements are not required to contain what has been listed on the label. [7] Additionally, oral joint supplements may have questionable bioavailability. [21]
One group of common alternative treatments are nutraceutical supplements. The most popular of these are joint supplements such as glucosamine, chondroitin, MSM, and hyaluronic acid. Related to joint supplements are various treatments for pain, viewed as alternatives to the common mainstream pain-reducing medications phenylbutazone, and banamine ...
A number of studies have measured the bioavailability of glucosamine after oral administration to horses. When given as a single oral dose (9 g) with or without chondroitin sulfate (3 g) to ten horses, glucosamine (hydrochloride) was detected in the blood with a maximum level of 10.6 ± 6.9 μg/mL at two hours after dosing. [47]
There are findings from Indian researchers that show an improvement of symptoms like pain, inflammation and swelling in patients by a combined intake of MSM and glucosamine. [31] Two other studies investigated the effects of MSM in combination with glucosamine and chondroitin (GC) on joint function. In the first study, the GC+MSM group saw ...
A significant amount of research has been performed on glycosaminoglycans, especially glucosamine and chondroitin, for the treatment of arthritis.These compounds are commonly marketed as nutritional supplements and numerous 'soft therapeutic claims' are made about their health benefits - especially in aging populations. [1]
Other joint medications, like hyaluronic acid and Adequan, may help alleviate the pain if the horse has mild bone spavin. However, they are less useful for treating moderate of severe cases. Nutritional supplements containing MSM, glucosamine, and other ingredients may also help horses with moderate bone spavin.
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