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Minoxidil, applied topically, is widely used for the treatment of hair loss. It may be effective in helping promote hair growth in both men and women with androgenic alopecia. [20] [21] About 40% of men experience hair regrowth after 3–6 months. [22] It is the only topical product that is FDA approved in America for androgenic hair loss. [20]
Research from 2016 looked at women with female pattern hair loss who didn’t respond to 5% minoxidil treatment. The women used 15% minoxidil for 12 weeks. The women used 15% minoxidil for 12 weeks.
Alfatradiol, also known as 17α-estradiol and sold under the brand names Avicis, Avixis, Ell-Cranell Alpha, and Pantostin, is a weak estrogen and 5α-reductase inhibitor medication which is used topically in the treatment of pattern hair loss (androgenic alopecia or pattern baldness) in men and women.
In normal skin, low-molecular weight hyaluronate (5 kDa) enhanced penetration into the epidermis. [17] Transepidermal water loss increased by 55.5% with low-molecular weight, and was reduced by 28% with crosslinked resilient, and by 16% with HMW. [18] Its efficacy against wrinkles has not been tested in clinical trials. [19]
Finasteride, sold under the brand names Proscar and Propecia among others, is a medication used to treat pattern hair loss and benign prostatic hyperplasia (BPH) in men. [6] It can also be used to treat excessive hair growth in women [7] and as gender-affirming treatment in trans women. [8]
Ketoconazole has additionally been used, in lower dosages, to treat hirsutism and, in combination with a GnRH analogue, male-limited precocious puberty. [25] In any case, the risk of hepatotoxicity with ketoconazole limits its use in all of these indications, especially in those that are benign such as hirsutism.
Isopropyl myristate is a polar emollient and is used in cosmetic and topical pharmaceutical preparations where skin absorption is desired. It is also used as a treatment for head lice. [2]
Coly-Mycin has a recommended dose of 2.5 to 5 mg/kg colistin base a day, which is equivalent to 6 to 12 mg/kg colistimethate sodium per day. For a 60 kg man, therefore, the recommended dose for Colomycin is 240 to 480 mg of colistimethate sodium, yet the recommended dose for Coly-Mycin is 360 to 720 mg of colistimethate sodium.
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