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Folinic acid, also known as leucovorin, is a medication used to decrease the toxic effects of methotrexate and pyrimethamine. [2] [3] It is also used in combination with 5-fluorouracil to treat colorectal cancer and pancreatic cancer, may be used to treat folate deficiency that results in anemia, and methanol poisoning.
South Gibson County High School is a school in Medina, Tennessee, serving students around Medina and Gibson, Tennessee. [3] [4] It opened in 2009, [5] to accommodate a growing population of students who lived in southern Gibson County, but were zoned to attend Gibson County High School. In 2021 another athletic facility was under development. [5]
The folate molecule is synthesized from pterin pyrophosphate, para-aminobenzoic acid (PABA), and glutamate through the action of dihydropteroate synthase and dihydrofolate synthase. Pterin is in turn derived in a series of enzymatically catalyzed steps from guanosine triphosphate (GTP), while PABA is a product of the shikimate pathway .
Portuguese: Ministério do Trabalho e Emprego: Agency overview; Formed: 2 May 1974; 50 years ago () Type: Ministry: Jurisdiction: Federal government of Brazil: Headquarters: Esplanada dos Ministérios, Bloco F Brasília, Federal District: Annual budget: $96.32 b BRL (2023) [1] Agency executives
The sialic acid family includes many derivatives of the nine-carbon sugar neuraminic acid, but these acids rarely appear free in nature.Normally they can be found as components of oligosaccharide chains of mucins, glycoproteins and glycolipids occupying terminal, nonreducing positions of complex carbohydrates on both external and internal membrane areas where they are very exposed and develop ...
The Integrated Medical Emergency System (Portuguese: Sistema Integrado de Emergência Médica) or SIEM, is centrally managed by the National Institute of Medical Emergencies (INEM). [1]
At sites of membrane budding or fusion, the membrane becomes or is highly curved. A major event in the budding of vesicles, such as transport carriers from the Golgi, is the creation and subsequent narrowing of the membrane neck. Studies have suggested that this process may be lipid-driven, and have postulated a central role for DAG due to its ...
Its reactions are representative of those of similar long chain, saturated fatty acids. It can be converted to the symmetrical fatty ketone called laurone (O=C(C 11 H 23) 2). [16] It transesterifies with vinyl acetate. [17] Treatment with sulfur trioxide gives the α-sulfonic acid. [18]