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In endemic regions, coccidioidomycosis is responsible for 20% of cases of community-acquired pneumonia. [13] Notable coccidioidomycosis signs and symptoms include a profound feeling of tiredness, loss of smell and taste, fever, cough, headaches, rash, muscle pain, and joint pain. [4] Fatigue can persist for many months after initial infection. [13]
Gifford was the first doctor to investigate a Californian disease called San Joaquin Valley Fever; a disease that cause joint pain and erythema multiforme. [8] [9] Coccidioidomycosis was first identified by an Argentinian medical student, Alejandro Posadas, in 1892, the year Gifford that was born. [10]
Disseminated coccidioidomycosis is a systemic infection caused by Coccidioides immitis. 15-20% of people with the infection develop skin lesions. [ 1 ] : 315 History of treatment
Coccidioides is a genus of dimorphic ascomycetes in the family Onygenaceae.Member species are the cause of coccidioidomycosis, also known as San Joaquin Valley fever, an infectious fungal disease largely confined to the Western Hemisphere and endemic in the Southwestern United States. [2]
Coccidioides posadasii is a pathogenic fungus that, along with Coccidioides immitis, is the causative agent of coccidioidomycosis, [1] or valley fever in humans.It resides in the soil in certain parts of the Southwestern United States, northern Mexico, and some other areas in the Americas, but its evolution was connected to its animal hosts.
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Primary pulmonary coccidioidomycosis is an infection caused by inhalation of Coccidioides immitis. [ 1 ] : 314 Once pulmonary symptoms subside, about 30% of women and 15% of men will have allergic skin manifestations in the form of erythema nodosum .