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Common side effects include sedation, fatigue, weight gain, constipation, and dry mouth. [11] Other side effects include low blood pressure with standing, seizures, a prolonged erection, high blood sugar, tardive dyskinesia, and neuroleptic malignant syndrome. [11] In older people with dementia, its use increases the risk of death. [11]
Many patients will not develop these side effects, although there is still a significant possibility of risks associated with Antipsychotic usage. The percentage of patients affected by side effects like Tardive dyskinesia is significantly high and estimated to be a 20-50% prevalence. [1] [2]
Since July 2023, three anti-amyloid medications have been FDA-approved for the treatment of Alzheimer’s disease with more in development. A potential and serious side effect of anti-amyloid ...
Antipsychotics by class Generic name Brand names Chemical class ATC code Typical antipsychotics; Acepromazine: Atravet, Acezine: phenothiazine: N05AA04
She noted that Alzheimer’s patients have a higher risk of death because of the natural course of the disease. In the large trial, less than 1% of patients died — the same rate whether they ...
Side-effects include a prolonged QT interval in the heart, which can be dangerous for patients with heart disease or those taking other drugs that prolong the QT interval. Lurasidone (Latuda) – Approved by the US FDA for schizophrenia and bipolar depression, and for use as schizophrenia treatment in Canada.
The FDA was initially set to decide about the treatment in March but delayed the decision in order to get more guidance from its advisory panel on whether the benefits outweighed the side effects.
Among the other side effects that have been suggested is that atypical antipsychotics increase the risk of cardiovascular disease. [54] Kabinoff and colleagues (2003) found that the increase in cardiovascular disease is seen regardless of the treatment received, and that it is instead caused by many different factors such as lifestyle or diet. [54]