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In bioinformatics, BLAST (basic local alignment search tool) [3] is an algorithm and program for comparing primary biological sequence information, such as the amino-acid sequences of proteins or the nucleotides of DNA and/or RNA sequences.
The NCBI assigns a unique identifier (taxonomy ID number) to each species of organism. [5] The NCBI has software tools that are available through web browsers or by FTP. For example, BLAST is a sequence similarity searching program. BLAST can do sequence comparisons against the GenBank DNA database in less than 15 seconds.
Linking and profiling sequence alignment data from NCBI-BLAST results with major sequence analysis servers/services: Nucleotide, peptide: 2010 SAM Local and global search with profile Hidden Markov models, more sensitive than PSI-BLAST: Both: Karplus K, Krogh A [15] 1999 SSEARCH Smith-Waterman search, slower but more sensitive than FASTA: Both ...
A sequence profiling tool in bioinformatics is a type of software that presents information related to a genetic sequence, gene name, or keyword input. Such tools generally take a query such as a DNA, RNA, or protein sequence or ‘keyword’ and search one or more databases for information related to that sequence.
BLAST (biotechnology), Basic Local Alignment Search Tool, an algorithm used in bioinformatics; Blast cell or precursor cell, in cytology, a type of partially differentiated, usually unipotent cell; Blast disease, a disease of cereal crops; Blast injury, a complex type of physical trauma resulting from direct or indirect exposure to an explosion
WU-BLAST with XDF was the first BLAST suite to support indexed-retrieval of NCBI standard FASTA-format sequence identifiers (including the entire range of NCBI identifiers); the first to allow retrieval of individual sequences in part or in whole, natively, translated or reverse-complemented; and the first able to dump the entire contents of a ...
The Entrez (/ ɒ n ˈ t r eɪ /) [1] Global Query Cross-Database Search System is a federated search engine, or web portal that allows users to search many discrete health sciences databases at the National Center for Biotechnology Information (NCBI) website. [2] The NCBI is a part of the National Library of Medicine (NLM), which is itself a ...
The web-based application of BLAT can be accessed from the UCSC Genome Bioinformatics Site. [8] Building the index is a relatively slow procedure. Therefore, each genome assembly used by the web-based BLAT is associated with a BLAT server, in order to have a pre-computed index available for alignments.