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Holt–Oram syndrome (also called atrio-digital syndrome, atriodigital dysplasia, cardiac-limb syndrome, heart-hand syndrome type 1, HOS, ventriculo-radial syndrome) is an autosomal dominant disorder that affects bones in the arms and hands (the upper limbs) and often causes heart problems. [1]
Is the most prevalent form of heart-hand syndrome. [1] It is an autosomal dominant disorder that affects bones in the arms and hands (the upper limbs) and may also cause heart problems. The syndrome includes an absent radial bone in the arms, an atrial septal defect, and a first degree heart block. [6]
People with TIC most often present with symptoms of congestive heart failure and/or symptoms related to their irregular heart rhythm. [1] Symptoms of congestive heart failure can include shortness of breath, ankle swelling, fatigue, and weight gain. [2] Symptoms of an irregular heart rhythm can include palpitations and chest discomfort. [2]
The most striking sign of Timothy syndrome type 1 is the co-occurrence of both syndactyly (about 0.03% of births) and long QT syndrome (1% per year) in a single patient. . Other common symptoms include cardiac arrhythmia (94%), heart malformations (59%), and autism or an autism spectrum disorder (80% who survive long enough for evaluati
Those affected by arrhythmogenic cardiomyopathy may not have any symptoms at all despite having significant abnormalities in the structure of their hearts. [6] If symptoms do occur, the initial presentation is often due to abnormal heart rhythms (arrhythmias) which in arrhythmogenic cardiomyopathy may take the form of palpitations, or blackouts. [7]
These three heart conditions are atrial fibrillation, heart failure and coronary heart disease. Prevention is key to a healthy heart and brain, says Fernando D. Testai, M.D., Ph.D., FAHA, chair of ...
Through exercise, there is increased input to the heart from the vagus nerve, which causes the heart to beat at a slower rate. This is manifested by a lower resting heart rate than may be seen in the average person. For elderly individuals, the rhythm may be caused by sinus node dysfunction. This is where the heart's pacemaker, the SA node, has ...
Symptoms commonly documented in patients history, classified according to cause: [2] [5] [6] [8] [9] Neurological - Dizziness, near syncope, and confusion. Heart failure - Dyspnea, orthopnea, paroxysmal nocturnal dyspnea, and edema. Hypotension - Seizure, mental status change, diaphoresis, and signs of orthostatic hypotension and shock.
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