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More than half of the world population will be obese by 2035, according to the 2023 World Obesity Atlas.. Obesity-related conditions include heart disease, stroke, certain cancers, and type 2 ...
Retatrutide: GLP-1, GIP, and glucagon receptor triple agonist In clinical trials 24 percent in a Phase II trial [77] Exenatide: Byetta GLP-1 receptor agonist: Approved for type 2 diabetes 2.5 kilograms (5.5 lb) [78] Cetilistat: Absorption inhibitor Not approved 1.5 kilograms (3.3 lb) [79] Tesofensine (NS2330)
Retatrutide (LY-3437943) is an experimental drug for obesity developed by American pharmaceutical company Eli Lilly and Company. It is a triple glucagon hormone receptor agonist ( GLP-1 , GIP , and GCGR receptors). [ 1 ]
At 48 weeks, for example, retatrutide had reduced levels of triglycerides by up to 40.6%, and levels of a protein called apoC-III involved in glucose metabolism and inflammation by 38%.
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Liraglutide, sold under the brand name Victoza among others, is an anti-diabetic medication used to treat type 2 diabetes, and chronic obesity. [6] [7] It is a second-line therapy for diabetes following first-line therapy with metformin.
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