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Pure water has a pH of 7 at 25 °C, meaning it is neutral. When an acid is dissolved in water, the pH will be less than 7, while a base , or alkali , will have a pH greater than 7. A strong acid, such as hydrochloric acid , at concentration 1 mol dm −3 has a pH of 0, while a strong alkali like sodium hydroxide , at the same concentration, has ...
Intracellular pH (pH i) is the measure of the acidity or basicity (i.e., pH) of intracellular fluid. The pH i plays a critical role in membrane transport and other intracellular processes. In an environment with the improper pH i , biological cells may have compromised function.
The pH at the end-point is greater than 7 and increases with increasing concentration of the acid, T A, as seen in the figure. In a titration of a weak acid with a strong base the pH rises more steeply as the end-point is approached. At the end-point, the slope of the curve of pH with respect to amount of titrant is a maximum.
The isoelectric point (pI, pH(I), IEP), is the pH at which a molecule carries no net electrical charge or is electrically neutral in the statistical mean. The standard nomenclature to represent the isoelectric point is pH(I). [1] However, pI is also used. [2] For brevity, this article uses pI.
In and of themselves, pH indicators are usually weak acids or weak bases. The general reaction scheme of acidic pH indicators in aqueous solutions can be formulated as: HInd (aq) + H 2 O (l) ⇌ H 3 O + (aq) + Ind − (aq) where, "HInd" is the acidic form and "Ind −" is the conjugate base of the indicator. Vice versa for basic pH indicators ...
When the pH is within the microbe's range, they grow and within that range there is an optimal growth pH. [4] Neutrophiles are adapted to live in an environment where the hydrogen ion concentration is at equilibrium. [2] They are sensitive to the concentration, and when the pH become too basic or acidic, the cell's proteins can denature. [4]
Acid–base homeostasis is the homeostatic regulation of the pH of the body's extracellular fluid (ECF). [1] The proper balance between the acids and bases (i.e. the pH) in the ECF is crucial for the normal physiology of the body—and for cellular metabolism. [1]
Studies of proteins adapted to low pH have revealed a few general mechanisms by which proteins can achieve acid stability. In most acid stable proteins (such as pepsin and the soxF protein from Sulfolobus acidocaldarius ), there is an overabundance of acidic residues which minimizes low pH destabilization induced by a buildup of positive charge.