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Chronic fatigue with a known cause is twice as common as idiopathic chronic fatigue. [6] Idiopathic chronic fatigue affects between 2.4% and 6.42% of patients, [26] with females more likely to be affected than men. [1] Age at onset is typically over 50 years of age. [13]
The fatigue must have lasted for 6 months or longer, and be present at least 50% of the time; Other symptoms are possible, such as muscle pain, mood problems, or sleep disturbance; Conditions known to cause severe fatigue and some mental conditions exclude a diagnosis. Post-infectious fatigue syndrome also requires evidence of a prior infection ...
The level of activity that triggers PEM, as well as the symptoms, vary from person to person, and within individuals over time. [6] Due to this variability, affected people may be unable to predict what will trigger it. [4] This variable, relapsing-remitting pattern can cause one's abilities to fluctuate from one day to the next. [1]
Research shows men are more likely than women to avoid—or delay—necessary medical care, even when their symptoms disrupt their lives or become chronic. ... the symptoms can progress over time ...
[10]: 3 Severity may change over time. Symptoms might get worse, improve, or the illness may go into remission for a period of time. [11] People who feel better for a period of time may overextend their activities, triggering PEM and a worsening of symptoms. [34] Those with severe and very severe ME/CFS experience more extreme and diverse symptoms.
PAIS symptoms are often non-specific and similar despite diverse prior infections. Symptoms commonly included in definitions of PAIS include post-exertional malaise, severe fatigue, neurocognitive and sensory symptoms, flu-like symptoms, unrefreshing sleep, muscle pain, and joint pain. Symptoms can vary among affected people. [1]
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Management of ME/CFS (myalgic encephalomyelitis/chronic fatigue syndrome) focuses on symptoms management, as no treatments that address the root cause of the illness are available. [ 1 ] : 29 Pacing, or regulating one's activities to avoid triggering worse symptoms, is the most common management strategy for post-exertional malaise .
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