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A particular interest in oat β-glucan arose after a cholesterol lowering effect from oat bran reported in 1981. [2] In 1997, the FDA approved of a claim that intake of at least 3.0 g of β-glucan from oats per day decreased absorption of dietary cholesterol and reduced the risk of coronary heart disease. The approved health claim was later ...
A 2021 meta-analysis of clinical trials concluded that oat beta-glucan with molecular weights greater than 300 kg/mol reduced incremental area-under-the-curve by 23%, peak blood glucose by 28%, and insulin by 22% in a dose-responsive fashion, with similar results in participants with or without diabetes. [24]
It has unique benefits on cholesterol and blood sugars. A 2021 study in the European Journal of Clinical Nutrition found that oat beta-glucan meaningfully improved blood sugars and insulin ...
A glucan is a polysaccharide derived from D-glucose, [1] linked by glycosidic bonds. Glucans are noted in two forms: alpha glucans and beta glucans. Many beta-glucans are medically important. They represent a drug target for antifungal medications of the echinocandin class.
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The product of the hydrolysis reaction is called a glucan, a linear polysaccharide made of up to 1200 glucose monomers, held together with glycosidic bonds. [1] Glucans are abundant in the endosperm cell walls of cereals such as barley , rye , sorghum , rice , and wheat . [ 1 ]
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Mixed-linkage glucan (MLG), sometimes incorrectly referred to as beta-glucan, is a hemicellulosic polysaccharide consisting of β-D(1-3) and β-D(1-4) linked glucosyl residues. MLG is highly prevalent within the Poales , where it has important properties in the diet .
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