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Bis(2-ethylhexyl) phthalate (di-2-ethylhexyl phthalate, diethylhexyl phthalate, diisooctyl phthalate, DEHP; incorrectly — dioctyl phthalate, DIOP) is an organic compound with the formula C 6 H 4 (CO 2 C 8 H 17) 2. DEHP is the most common member of the class of phthalates, which are used as plasticizers.
This includes Bis(2-ethylhexyl) phthalate (DEHP or DOP), which has long been the most widely used phthalate, with commercial production dating back to the 1930s. [ 16 ] [ 17 ] In the EU, the use of DEHP is restricted under REACH and it can only be used in specific cases if an authorisation has been granted; similar restrictions exist in many ...
TBPH is the brominated analogue of bis(2-ethylhexyl) phthalate (DEHP). Much like TBPH, DEHP has been widely used as a plasticizer , however unlike TBPH, it is currently a restricted substance due to its endocrine disrupting properties and reproductive toxicity . [ 6 ]
In combination with palbociclib and fulvestrant for the treatment of adults with endocrine-resistant, PIK3CA-mutated, hormone receptor (HR)-positive, human epidermal growth-factor receptor 2 (HER2)-negative, locally advanced or metastatic breast cancer, as detected by an FDA-approved test, following recurrence on or after completing adjuvant ...
The drug or other substance has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse of the drug or other substances may lead to severe psychological or physical dependence. The complete list of Schedule II substances is as follows.
The enzyme bis(2-ethylhexyl)phthalate esterase (EC 3.1.1.60) catalyzes the reaction bis(2-ethylhexyl)phthalate + H 2 O 2-ethylhexyl phthalate + 2-ethylhexan-1-ol Action of the enzyme. This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds.
Bis(2-ethylhexyl) phthalate (DEHP) also commonly known as (dioctyl phthalate, [13] DOP or diethylhexyl phthalate), historically used in flooring materials, medical devices, myriad consumer products, and high explosives, such as Semtex. DEHP was the most common plasticizer for decades and still holds that title globally even as it has largely ...
Bis(2-ethylhexyl) terephthalate commonly abbreviated DEHT (Dioctyl terephthalate or DOTP), is an organic compound with the formula C 6 H 4 (CO 2 C 8 H 17) 2. It is a non- phthalate plasticizer , being the diester of terephthalic acid and the branched-chain 2-ethylhexanol , which is often generically referred to as octyl.