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Enzyme multiplied immunoassay technique (EMIT) is a common method for qualitative and quantitative determination of therapeutic and recreational drugs and certain proteins in serum and urine. [ 1 ] It is an immunoassay in which a drug or metabolite in the sample competes with a drug/metabolite labelled with an enzyme, to bind to an antibody.
Side effects include hyperthermia and decrease in white blood cell count. These effects tend to be mild and transient. It is a immunostimulant in the interferon family. [3] The feline interferon "omega" gene was first cloned in 1992. [4] It was first produced in silkworms by Ueda and coworkers in 1993.
Virbac is a French company dedicated to animal health located in Carros, near Nice. It was founded in 1968 by veterinarian Pierre-Richard Dick. The company is the 6th [1] the largest veterinarian pharmaceutical group with a turnover of 1,247 million euros in 2023 (59% companion animal and 41% food producing animal).
Like Δ 9-THC, 11-hydroxy-THC is a partial agonist at the cannabinoid receptor CB 1, but with significantly higher binding affinity (K i = 0.37 nM compared to Δ 9-THC K i = 35 nM). [7] With respect to cAMP inhibition at CB 1 it displays a similar efficacy to that of Δ 9 -THC (EC 50 = 11 nM vs. EC 50 = 5.2 nM, respectively), but a lower ...
The endogenous cannabinoid system includes cannabinoid receptors, their endogenous ligands (endocannabinoids) and enzymes for their synthesis and degradation. [13]There are two main receptor types associated with the endocannabinoid signaling system: cannabinoid receptor 1 (CB 1) and 2 (CB 2).
Selamectin, sold under the brand name Revolution, among others, is a topical parasiticide and anthelminthic used on dogs and cats. [2] It treats and prevents infections of heartworms, fleas, ear mites, sarcoptic mange (scabies), and certain types of ticks in dogs, and prevents heartworms, fleas, ear mites, hookworms, and roundworms in cats.
Enzyme replacement therapy (ERT) is a medical treatment which replaces an enzyme that is deficient or absent in the body. [1] Usually, this is done by giving the patient an intravenous (IV) infusion of a solution containing the enzyme. [1]
SARS-CoV-2 and HIV-1 have similarities—notably both are RNA viruses—but there are important differences. As a retrovirus, HIV-1 can insert a copy of its RNA genome into the host's DNA, making total eradication more difficult. [156] The virus is also highly mutable making it a challenge for the adaptive immune system to develop a response.
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