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Enzyme replacement therapy (ERT) is a medical treatment which replaces an enzyme that is deficient or absent in the body. [1] Usually, this is done by giving the patient an intravenous (IV) infusion of a solution containing the enzyme. [1]
Enzyme multiplied immunoassay technique (EMIT) is a common method for qualitative and quantitative determination of therapeutic and recreational drugs and certain proteins in serum and urine. [ 1 ] It is an immunoassay in which a drug or metabolite in the sample competes with a drug/metabolite labelled with an enzyme, to bind to an antibody.
These are achieved at lower doses, because many synthetic cannabinoids are more potent than marijuana, and users are often unaware of exactly what they are getting and how potent it is. [62] For example, Δ 9-THC has an EC 50 of 250 nM at CB 1 and 1157 nM at CB 2, whereas PB-22 has an EC 50 of 5.1 nM at CB 1 and 37 nM at CB 2. [8]
Virbac is a French company dedicated to animal health located in Carros, near Nice. It was founded in 1968 by veterinarian Pierre-Richard Dick. The company is the 6th [1] the largest veterinarian pharmaceutical group with a turnover of 1,247 million euros in 2023 (59% companion animal and 41% food producing animal).
The enzyme carboxylesterase (or carboxylic-ester hydrolase, EC 3.1.1.1; systematic name carboxylic-ester hydrolase) catalyzes reactions of the following form: [1]. a carboxylic ester + H 2 O an alcohol + a carboxylate
There are several treatment guidelines for HIV-1 infected adults in the developed world (that is, those countries with access to all or most therapies and laboratory tests). In the United States there are both the International AIDS Society-USA (IAS-USA) (a 501(c)(3) not-for-profit organization in the US) [ 47 ] as well as the US government's ...
The largest scale application of transesterification is in the synthesis of polyesters. [3] In this application, diesters undergo transesterification with diols to form macromolecules. For example, dimethyl terephthalate and ethylene glycol react to form polyethylene terephthalate and methanol, which is evaporated to drive the reaction forward.
The 1,1-diaryl group is also present in derivatives such as the benzodioxoles and hydantoins. [2] [20] Acyclic analogs have also been reported. These analogs contain a 1,2-diaryl motif which corresponds to the 1,5-diaryl substituents of rimonabant. [2] An example of an acyclic analog is taranabant (MK-0364) developed by Merck. [27]
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