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CTLA-4 is a member of the immunoglobulin superfamily that is expressed by activated T cells and transmits an inhibitory signal to T cells. CTLA-4 is homologous to the T-cell co-stimulatory protein, CD28, and both molecules bind to CD80 and CD86, also called B7-1 and B7-2 respectively, on antigen-presenting cells. CTLA-4 binds CD80 and CD86 with ...
A simple smiley. This is a list of emoticons or textual portrayals of a writer's moods or facial expressions in the form of icons.Originally, these icons consisted of ASCII art, and later, Shift JIS art and Unicode art.
Emoji Unicode name Codepoints Added in Unicode block Meaning 😀 Grinning Face U+1F600: Emoji 1.0 in 2015 Emoticons: Grinning: 😂 Face with Tears of Joy U+1F602: Emoji 1.0 in 2015 Emoticons see Face with Tears of Joy emoji: 😍 Smiling Face with Heart-Shaped Eyes U+1F60D: Emoji 1.0 in 2015 Emoticons see Face with Heart Eyes emoji: 🕴️
An emoji (/ ɪ ˈ m oʊ dʒ iː / ih-MOH-jee; plural emoji or emojis; [1] Japanese: 絵文字, Japanese pronunciation:) is a pictogram, logogram, ideogram, or smiley embedded in text and used in electronic messages and web pages.
With the exception of the information emoji (ℹ), the trademark emoji (™️) and the "m" emoji (Ⓜ️), [citation needed] for an emoji to work as a domain name, it must be converted into so-called "Punycode". Punycode is a character encoding method used for internationalized domain names (IDNs). This representation is used when registering ...
There's a new heart emoji on the block (since 2022), and its light blue hue, according to Emojipedia, epitomizes "love, friendship, feelings of warmth, and the color blue." Cheerful, if not ...
The second most-popular emoji is the heart-shaped-eyes face. It can stand for "gorgeous," "goregous" or "gorgous." Apparently "gorgeous" is a really hard word to spell.
Abatacept is a soluble CTLA-4 analog that prevents antigen-presenting cells (APCs) from delivering the co-stimulatory signal. This prevents the T cells from being fully activated, and even downregulates them. Simple signaling without co-stimulation allows the cell to recognize the primary signal as "self" and not ramp-up responses for future ...