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0.343 mPa·s at 25 °C Surface tension [2] 29.29 dyn/cm Thermodynamic properties. Phase behavior Triple point [3] ... log 10 of Acetonitrile vapor pressure.
Bioavailability is 91% at the standard subcutaneous dose but 24% at the standard oral dose; the standard oral dose is higher to partially compensate for incomplete bioavailability. [ 5 ] [ 18 ] It binds to plasma proteins at a rate of 99.5%; it has a low volume of distribution (9 L/kg) and is thus not extensively absorbed.
The metabolism of acetonitrile is much slower than that of other nitriles, which accounts for its relatively low toxicity. Hence, one hour after administration of a potentially lethal dose, the concentration of cyanide in the rat brain was 1 ⁄ 20 that for a propionitrile dose 60 times lower (see table). [24]
Sigma Advanced Genetic Engineering (SAGE) Labs is a division within Sigma-Aldrich that specializes in genetic manipulation of in vivo systems for special research and development applications. It was formed in 2008 to investigate zinc finger nuclease technology and its application for disease research models.
Euthasol has the following composition: 390 mg/mL pentobarbital sodium, 50 mg/mL phenytoin sodium, 10% ethyl alcohol, 18% propylene glycol, 0.003688 mg/mL Rhodamine B, 2% benzyl alcohol, water and sodium hydroxide and hydrochloric acid as needed to achieve desired pH.
Up to $50 million in grants for research into nonsurgical sterilization methods has been committed by the foundation. A $25 million Michelson Prize has been offered for the first entity to develop a single-dose, permanent, nonsurgical sterilizing agent that is safe and effective in male and female cats and dogs. [14] [15]
The term dosage form may also sometimes refer only to the pharmaceutical formulation of a drug product's constituent substances, without considering its final configuration as a consumable product (e.g., capsule, patch, etc.). Due to the somewhat ambiguous nature and overlap of these terms within the pharmaceutical industry, caution is ...
It is used for operative and accident-related pain in small mammals such as dogs, cats, ferrets, coatis, raccoons, mongooses, various marsupials, some rodents and perhaps some larger birds. Although butorphanol is commonly used for pain relief in reptiles, no studies (as of 2014) have conclusively shown that it is an effective analgesic in ...
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